D0184

2′-Deoxyuridine 5′-triphosphate sodium salt solution

100 mM in H₂O

• Sinônimo(s): dUTP sodium salt
• Fórmula empírica (Notação de Hill): C₉H₁₅N₂O₁₄P₃ · xNa⁺
• Número CAS: 94736-09-1
• Peso molecular: 468.14 (free acid basis)
• Número MDL: MFCD01630759
• Código UNSPSC: 41106305
• ID de substância PubChem: 24893218
• NACRES: NA.52

Propriedades

• Ensaio: ≥99%
• forma: liquid
• concentração: 100 mM in H₂O
• cor: colorless
• atividade externa: DNase, RNase, none detected
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
• chave InChI: FVFWWPFKJNTHIQ-UHFFFAOYSA-N

Descrição

Descrição geral

2′-Deoxyuridine 5′-triphosphate (dUTP) is incorporated into DNA during DNA synthesis. It is one of the main intermediate during pyrimidine nucleotide biosynthesis. It is one of the sources of uracil in DNA. Deoxyuridine 5′-triphosphate nucleotidohydrolase suppresses the incorporation of dUTP into DNA. It converts dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP).

Aplicação

2′-Deoxyuridine 5′-triphosphate sodium salt solution has been used in the mouse genomic DNA amplification by polymerase chain reaction (PCR). It is also suitable for conjunction with uracil DNA glycosylase to prevent carryover contamination in PCR. The dUTP is substituted for dTTP in the PCR reaction.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable