KELLY Cell Line human

92110411, human brain, Neuronal

• Sinônimo(s): NB19 Cells, NB19-RIKEN Cells
• Código UNSPSC: 41106514

Propriedades

• Nome do produto: KELLY Cell Line human, 92110411, neuroblastoma
• fonte biológica: human brain
• modo de crescimento: Adherent
• cariótipo: Not specified
• morfologia: Neuronal
• produtos: N-myc RNA or protein
• receptores: Not specified
• técnica(s): cell culture | mammalian: suitable
• doença(s) relevante(s): cancer
• Condições de expedição: dry ice
• temperatura de armazenamento: −196°C

Descrição

Origem de linhagem celular

Human neuroblastoma

Descrição de linhagem celular

The cells possess a genomic amplification of the N-myc gene and express elevated levels of N-myc RNA or protein.

Aplicação

KELLY cell line has been used to study the role of polysialic acid (PSA) in controlling tumor cell growth and differentiation by interfering with neural cell adhesion molecule (NCAM) signaling. It has also been used to study the role of protein tyrosine phosphatase SHP1 in inhibiting Ret oncogene activity.

Meio de cultura

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Rotina de subcultura

Split sub-confluent cultures (70-80%) 1:5 to 1:20 i.e. seeding at 5x1,000-2x10,000 cells/cm² using 0.25% trypsin or trypsin/EDTA; 5% CO₂; 37°C.

Outras notas

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