C7673
Monoclonal Anti-CD14 antibody produced in mouse
clone UCHM-1, purified immunoglobulin, buffered aqueous solution
Sinônimo(s):
Monoclonal Anti-CD14
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
mouse
conjugado
unconjugated
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
UCHM-1, monoclonal
Formulário
buffered aqueous solution
peso molecular
antigen 55 kDa
reatividade de espécies
human
técnica(s)
flow cytometry: 5 μL using 1 × 106 cells
Isotipo
IgG2a
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... CD14(929)
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Especificidade
The epitope recognized by this clone is sensitive to routine formalin fixation and paraffin embedding. Cryostat sections, post-fixed in formalin can be stained.
3rd Workshop: code no. 203
4th Workshop: code no. M24
3rd Workshop: code no. 203
4th Workshop: code no. M24
Imunogênio
human thymocytes followed by peripheral blood T cells.
Aplicação
Monoclonal Anti-CD14 antibody produced in mouse is suitable for the following applications:
- Flow cytometry at a dilution of 5μL using 1 × 106 cells
- Immunofluorescence.
- Immunoblotting.
Ações bioquímicas/fisiológicas
CD14 gene has an important role during signaling of the innate immune response and in the detection of inflammatory pathogens. It also plays an important role in recognizing tuberculosis (TB) disease and it can be used as a potential biomarker for predicting the prognosis of breast invasive ductal carcinoma with LN+ER/PR-Her2+. It is also associated with asthma, croup and allergy.
Descrição-alvo
CD14 is a phosphoinositol-linked, single-chain, human cell surface glycoprotein antigen which is found on most human peripheral blood monocytes, granulocytes and dendritic reticulum cells, and some tissue macrophages. CD14 may also be present on B cells. Soluble forms of CD14 are present in serum and urine. The antigen functions as an acceptor for LPS-binding protein complexes.
forma física
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
nwg
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Weifeng He et al.
PloS one, 8(9), e75366-e75366 (2013-10-03)
In clinical practice, breast cancers with lymph node positive, ER/PR-negative and overexpressed human epidermal growth factor receptor 2 (LN+ER/PR-Her2+) have high risk of recurrence, but the effective biomarkers of prognostic for this type tumor are still lacking. Since breast cancers
Barbara M Rothen-Rutishauser et al.
American journal of respiratory cell and molecular biology, 32(4), 281-289 (2005-01-11)
A novel triple co-culture model of the human airway barrier was designed to simulate the cellular part of the air-blood barrier of the respiratory tract represented by macrophages, epithelial cells, and dendritic cells. When epithelial cells (A549 cells) were grown
J Zhao et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 17(11), 1472-1478 (2013-10-16)
CD14 plays an important role in recognising the tuberculosis (TB) antigen and initiating immune response. CD14-159C/T polymorphism has been reported to be associated with susceptibility to TB in some, but not all studies. To comprehensively evaluate the correlation between CD14-159C/T
Donna C Rennie et al.
Disease markers, 35(6), 765-771 (2013-12-19)
The CD14 gene has an important role in the detection of inflammatory provoking pathogens and in the ensuing signaling of the innate immune response. We assessed the role of CD14 C-159T, G-1359T in the expression of asthma, croup, and allergy
Elena M V de Cavanagh et al.
American journal of physiology. Heart and circulatory physiology, 319(4), H744-H752 (2020-08-17)
Patients presenting with classical cardiovascular risk factors within acceptable or average value ranges often develop cardiovascular disease, suggesting that other risk factors need to be considered. Considering that endothelial progenitor cells (EPCs) contribute to endothelial repair, we investigated whether EPCs
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