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C2488

Sigma-Aldrich

Citrate Buffer Solution, 0.09 M

Sinônimo(s):

Citric Acid Buffer Solution

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About This Item

Código UNSPSC:
12161700
eCl@ss:
32129211
NACRES:
NA.25

descrição

Contains 1% chloroform
pH 4.8 at 25 °C.

Nível de qualidade

Formulário

solution

concentração

0.09 M

pH

4.8 (25 °C)

aplicação(ões)

diagnostic assay manufacturing

temperatura de armazenamento

2-8°C

Descrição geral

Citrate Buffer Solution, 0.09 M, is a high-quality biochemical buffer solution commonly employed in various research applications. Its applications include use in acid phosphatase reactions alongside p-nitrophenyl phosphate (pNPP) enzyme substrate. Citrate Buffer is also used for the isolation of RNA from cells and tissues. In addition, it is also used as a background electrolyte for separating sulfonamides utilizing capillary zone electrophoresis. With its superior buffering capacity and ability to maintain a stable pH, Citrate Buffer Solution, 0.09 M is an excellent choice for any researcher in need of reliable performance.

Aplicação

Citrate Buffer Solution, 0.09 M has been used as a heat-induced antigen retriever on formalin-fixed paraffin-embedded (FFPE) tissue sections during immunohistochemistry (IHC) experiments. It has also been used in the preparation of hybridization solutions for fluorescence in situ hybridization (FISH) procedures.

Outras notas

Unit definition: One unit of acid phosphatase will hydrolyze 1.0 μmole of p-nitrophenyl phosphate per, minute at pH 4.8 at 37 °C.

Pictogramas

Health hazard

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Carc. 2 - STOT RE 2 Oral

Órgãos-alvo

Liver,Kidney

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Primary oral malignant melanoma (POMM) is a rare type of malignancy with a very poor prognosis, the molecular pathogenesis of which remains elusive. The aim of this study was to assess the expression status of signal transducer and activator of
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Chromosome 16p11.2 duplications dramatically increase risk for schizophrenia, but the mechanisms remain largely unknown. Here, we show that mice with an equivalent genetic mutation (16p11.2 duplication mice) exhibit impaired hippocampal-orbitofrontal and hippocampal-amygdala functional connectivity. Expression of schizophrenia-relevant GABAergic cell markers
Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity.
Kukic I, Kelleher SL, and Kiselyov K
Journal of Cell Science, 127(Pt 14), 3094-3103 (2014)

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