C167

Cholera Toxin B subunit

solid

• Sinônimo(s): CTB
• Número MDL: MFCD02356522
• Código UNSPSC: 12352200
• ID de substância PubChem: 329774903
• NACRES: NA.77

Propriedades

• forma: solid
• Nível de qualidade: 200
• peso molecular: ~12 kDa
• cor: white
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CCOc1ccccc1C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F
• InChI: 1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
• chave InChI: YDXZSNHARVUYNM-UHFFFAOYSA-N

Descrição

Descrição geral

Cholera Toxin B subunit is secreted by Vibrio cholerae. It is a pentamer and is nontoxic in nature.

Aplicação

Cholera Toxin B subunit has been used as a tracer to study the ascending projections of the nuclei of the descending trigeminal tract (nTTD) in the zebra finch.

Ações bioquímicas/fisiológicas

Cholera Toxin B subunit stimulates both systemic and mucosal antibody production in animals and humans. CTB functions as an oral subunit vaccine for cholera, which is associated with acute watery diarrhoea.

The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.

Atenção

Do not freeze.

Reconstituição

When reconstituted in 0.25 mL distilled water, the compound contains 500 μg of protein in 0.01 M sodium phosphate at pH 7.5.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable