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Key Documents

C1138

Sigma-Aldrich

ι-Carrageenan

commercial grade, Predominantly iota carrageenan

Sinônimo(s):

Vegetable gelatin

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About This Item

Número CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.25

fonte biológica

algae (Eucheuma spinosum)

grau

commercial grade

forma

powder

cor

beige

faixa de pH útil

8.0 - 10.5

solubilidade

water: soluble ~5 g/L

temperatura de armazenamento

room temp

InChI

1S/C24H38O31S4/c25-1-5-12(52-56(31,32)33)9(27)10(28)22(46-5)49-14-8-4-44-18(14)20(55-59(40,41)42)24(48-8)51-16-11(29)23(47-6(2-26)15(16)53-57(34,35)36)50-13-7-3-43-17(13)19(21(30)45-7)54-58(37,38)39/h5-30H,1-4H2,(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)/p-4/t5-,6-,7-,8-,9-,10-,11-,12+,13+,14+,15+,16-,17+,18+,19-,20-,21+,22+,23+,24-/m1/s1

chave InChI

QIDSWKFAPCTSKL-RRQHLKGPSA-J

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Descrição geral

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.

Aplicação

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-,and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities. ι-Carrageenan may be used to help define the role of carrageenan sulfation levels in physicochemical, biochemical, biological and pharmacological responses.

Nota de preparo

Blended from various seaweeds to produce flexible gels.

Outras notas

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type N95 (US)


Certificados de análise (COA)

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Jalles A Batista et al.
Carbohydrate polymers, 99, 59-67 (2013-11-28)
The sulfated polysaccharide (PLS) fraction of Agardhiella ramosissima was characterized by microanalysis, infrared spectroscopy, NMR and gas-liquid-chromatography-mass-spectrometry. The main constituent of PLS was the ι carrageenan. The monosaccharide composition of the PLS showed galactose, 3,6-anhydrogalactose and 6-O-methylgalactose. The PLS (30
Ritsu Nishimura et al.
Journal of medical and dental sciences, 60(1), 1-8 (2013-08-07)
Various gelatinizers, which facilitate oral ingestion, are employed in patients with dysphagia. The purpose of this study was to histologically clarify the influence of various gelatinizers on the lung, using rats. We administered 0.2 ml/kg of 0.1% xanthangam, a 0.25%
Kihyuck Kwak et al.
PloS one, 9(5), e97232-e97232 (2014-05-13)
The licensed human papillomavirus (HPV) vaccines elicit type-restricted immunity but do not target cutaneous HPV types of the beta genus that are associated with non-melanoma skin cancer in immune-compromised patients, and it is unclear if these diverse types share a
Andrew G Hettle et al.
Structure (London, England : 1993), 26(5), 747-758 (2018-04-24)
Sulfatases play a biologically important role by cleaving sulfate groups from molecules. They can be identified on the basis of signature sequences within their primary structures, and the largest family, S1, has predictable features that contribute specifically to the recognition
Andreas Sichert et al.
Nature microbiology, 5(8), 1026-1039 (2020-05-27)
Brown algae are important players in the global carbon cycle by fixing carbon dioxide into 1 Gt of biomass annually, yet the fate of fucoidan-their major cell wall polysaccharide-remains poorly understood. Microbial degradation of fucoidans is slower than that of other

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