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Key Documents

180947

Sigma-Aldrich

Alginic acid sodium salt

powder

Sinônimo(s):

Algin, Sodium alginate

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12162002
NACRES:
NA.23

fonte biológica

algae (marine)

forma

powder

viscosidade

15-25 cP, 1 % in H2O

InChI

1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1/t1-,2-,3-,4?,6+;/m0./s1

chave InChI

MSXHSNHNTORCAW-MPGIDXPLSA-M

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Descrição geral

Alginic acid sodium is a gelling and nontoxic anionic polysaccharide. The carboxylic acid groups on the alginic acid chain, renders it insoluble in water.However, converting alginic acid to its sodium form, enables it to solubilize in water easily.

Aplicação

Alginic acid sodium is used:
  • in combination with chitosan, to fabricate a biodegradable porous scaffold for bone tissue engineering.
  • to study the characteristics of a modified amphiphilic alginate derivative
  • to the study the impact of alginate on the rate of lipid digestion by employing an in vitro digestion model
  • in the preparation of alginate hydrogels
  • as encapsulating agents of microparticles of β-galactosidae

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Visite a Biblioteca de Documentos

Thao Thi Thu Vu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(7), 1980-1988 (2012-08-14)
Alginate hydrogels possess tunable mechanical properties that can mimic soft marrow tissue and present three-dimensional (3D) cues. This study evaluates its utility for supporting leukemic cell growth in vitro and its impact on cell survival, growth, and differentiation. Our results
Microencapsulation of ?-galactosidase with different biopolymers by a spray-drying process
Estevinho BN, et al.
Food Research International, 64, 134-140 (2014)
Teegarden DM
Polymer Chemistry: Introduction to an Indispensable Science (2004)
Zhensheng Li et al.
Biomaterials, 26(18), 3919-3928 (2005-01-01)
A biodegradable scaffold in tissue engineering serves as a temporary skeleton to accommodate and stimulate new tissue growth. Here we report on the development of a biodegradable porous scaffold made from naturally derived chitosan and alginate polymers with significantly improved
Role of calcium and calcium-binding agents on the lipase digestibility of emulsified lipids using an in vitro digestion model
Hu M, et al.
Food Hydrocolloids, 24(8), 719-725 (2010)

Artigos

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

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