C0563
Cardiolipin sodium salt from bovine heart
≥97% (TLC), lyophilized powder
Sinônimo(s):
Diphosphatidylglycerol
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About This Item
Produtos recomendados
fonte biológica
bovine heart
Nível de qualidade
Ensaio
≥97% (TLC)
forma
lyophilized powder
tipo de lipídio
phosphoglycerides
Condições de expedição
ambient
temperatura de armazenamento
−20°C
Descrição geral
Cardiolipin is localized in the inner membrane of mitochondria. It contains 18 carbon atoms, 3-phosphatidyl groups connected via a glycerol bridge. Cardiolipin is an important component of ATP synthase enzyme.
Aplicação
Cardiolipin sodium salt from bovine heart has been used:
- as a phospholipid standard in thin layer chromatography for the quantification of total mitochondrial lipids of Neurospora crassa(89)
- as an internal standard in reverse phase high performance liquid chromatography (RP-HPLC) for quantification of bacterial lipid extracts(90)
- as an antigen to evaluate IgM reaction in systemic lupus erythematosus (SLE) patients(91)
Ações bioquímicas/fisiológicas
Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component. Inhibits cell attachment of fibronectin, vitronectin and Type I collagen.
Embalagem
packaged under argon
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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The Journal of biological chemistry, 289(46), 31708-31718 (2014-10-08)
Bax is a pro-apoptotic Bcl-2 family protein. The activated Bax translocates to mitochondria, where it forms pore and permeabilizes the mitochondrial outer membrane. This process requires the BH3-only activator protein (i.e. tBid) and can be inhibited by anti-apoptotic Bcl-2 family
Scientific reports, 7(1), 2060-2060 (2017-05-19)
Cardiolipin (CL) is a unique mitochondrial phospholipid that, in skeletal muscle, is enriched with linoleic acid (18:2n6). Together, CL content and CL 18:2n6 composition are critical determinants of mitochondrial function. Skeletal muscle is comprised of slow and fast fibers that
Effects of pure n-alkanes and crude oil on bacterial phospholipid classes and molecular species determined by electrospray ionization mass spectrometry
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 822(1-2), 40-53 (2005)
Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA
Immunology, 141(2), 276-285 (2014)
Analysis of mutations in Neurospora crassa ERMES components reveals specific functions related to beta-barrel protein assembly and maintenance of mitochondrial morphology
PLoS ONE, 8(8), e71837-e71837 (2013)
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