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B1434

Sigma-Aldrich

BMP7, human

>95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

Sinônimo(s):

BMP-7, OP-1, Osteogenic protein 1

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About This Item

Número MDL:
MFCD03702812
Código UNSPSC:
12352202
NACRES:
NA.32

product name

Bone Morphogenetic Protein 7 human, >95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

fonte biológica

human

Nível de qualidade

100

recombinante

expressed in CHO cells

Ensaio

>95% (SDS-PAGE)

forma

lyophilized powder

potência

0.2-0.6 μg/mL ED50

peso molecular

monomer calculated mol wt 15.7 kDa
 18-20 kDa by SDS-PAGE (reducing)
 30-40 kDa by SDS-PAGE (non-reducing)

embalagem

pkg of 10 μg

condição de armazenamento

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

nº de adesão UniProt

P18075

temperatura de armazenamento

−20°C

Informações sobre genes

human ... BMP7(655)

Categorias relacionadas

Ações bioquímicas/fisiológicas

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

forma física

Lyophilized from 50.0 μl of a 0.2 μm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 μg bovine serum albumin per 1μg of cytokine.

Nota de análise

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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A J Celeste et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(24), 9843-9847 (1990-12-01)
Characterization of the polypeptides present in bone-inductive protein extracts from bovine bone has led to the cloning of seven regulatory molecules, six of which are distantly related to transforming growth factor beta. The three human bone morphogenetic proteins (BMPs) we
A H Reddi
Nature biotechnology, 16(3), 247-252 (1998-04-07)
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It has formed the basis for the emerging discipline of tissue engineering, which uses principles of molecular developmental biology and morphogenesis gleaned through
Yan Wang et al.
Experimental and molecular pathology, 98(3), 393-402 (2015-03-17)
This study presented the effect of bone morphogenic protein-7 (BMP-7) inhibiting epithelial-mesenchymal transition (EMT) in silicosis model. In vivo, Wistar rats were exposed to silica by intratracheal instillation. Seven days later rats were treated with BMP-7. Rats were sacrificed at
Endre Kristóf et al.
Scientific reports, 5, 12540-12540 (2015-07-28)
Laser-scanning cytometry is presented as a tool allowing population scale analysis of ex vivo human brown adipogenic differentiation. It combines texture analysis and detection of Ucp1 protein content in single brown adipocytes of mixed cell populations with gene expression pattern
Pilar González-Gómez et al.
Oncotarget, 6(13), 10950-10963 (2015-04-11)
Glioblastoma tumor initiating cells are believed to be the main drivers behind tumor recurrence, and therefore therapies that specifically manage this population are of great medical interest. In a previous work, we synthesized controlled release microspheres optimized for intracranial delivery
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