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A9719

Sigma-Aldrich

Arachidonyl-2′-chloroethylamide hydrate

≥97% (HPLC), oil

Sinônimo(s):

ACEA

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About This Item

Fórmula empírica (Notação de Hill):
C22H36ClNO · xH2O
Número CAS:
220556-69-4
Peso molecular:
365.98 (anhydrous basis)
Número MDL:
MFCD02683581
Código UNSPSC:
51111800
ID de substância PubChem:
24891489
NACRES:
NA.77

Nível de qualidade

100

Ensaio

≥97% (HPLC)

Formulário

oil

controle de medicamentos

regulated under CDSA - not available from Sigma-Aldrich Canada

condição de armazenamento

desiccated

cor

brown-red

solubilidade

DMSO: soluble
H2O: insoluble

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCCl

InChI

1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-

chave InChI

SCJNCDSAIRBRIA-DOFZRALJSA-N

Informações sobre genes

mouse ... Cnr1(12801) , Cnr2(12802)
rat ... Cnr1(25248)

Ações bioquímicas/fisiológicas

Potent and selective neuronal CB1 cannabinoid receptor agonist.

Características e benefícios

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Atenção

Photosensitive; store under argon or nitrogen.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
047M4601V
045M4609V
034M4603V
123M4604V
023M4615V

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

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Visite a Biblioteca de Documentos

Yahya I Asiri et al.
Anesthesia and analgesia, 127(2), 548-555 (2017-10-11)
Development of new analgesics is limited by shortcomings of existing preclinical screening assays such as wide variations in response, suitability for a narrow range of analgesics, and propensity to induce tissue damage. Our aim was to determine the feasibility of
Chris L Baker et al.
British journal of pharmacology, 142(8), 1361-1367 (2004-07-28)
The vasoactive effects of the synthetic cannabinoid (CB) arachidonyl-2-chloroethylamide (ACEA) was tested in the knee joints of urethane-anaesthetised rats. Experiments were also performed to determine whether these vasomotor responses could be blocked by the selective CB(1) receptor antagonists AM251 (N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide)
C J Hillard et al.
The Journal of pharmacology and experimental therapeutics, 289(3), 1427-1433 (1999-05-21)
Two subtypes of the cannabinoid receptor (CB1 and CB2) are expressed in mammalian tissues. Although selective antagonists are available for each of the subtypes, most of the available cannabinoid agonists bind to both CB1 and CB2 with similar affinities. We
Kristina B V Døssing et al.
Genes, 9(7) (2018-07-06)
Somatostatin (SST) analogues are used to control the proliferation and symptoms of neuroendocrine tumors (NETs). MicroRNAs (miRNA) are small non-coding RNAs that modulate posttranscriptional gene expression. We wanted to characterize the miRNAs operating under the control of SST to elucidate
Tamás Oláh et al.
The Journal of physiology, 594(24), 7381-7398 (2016-10-28)
Marijuana was found to cause muscle weakness, although the exact regulatory role of its receptors (CB1 cannabinoid receptor; CB1R) in the excitation-contraction coupling (ECC) of mammalian skeletal muscle remains unknown. We found that CB1R activation or its knockout did not
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