A4980
Abz-FRK(Dnp)P-OH trifluoroacetate salt
≥95% (HPLC), film
Sinônimo(s):
o-Aminobenzoic acid-FRK(Dnp)P-OH, o-aminobenzoic acid-Phe-Arg-Lys(DNP)-Pro-OH trifluoroacetate salt, Abz-Phe-Arg-Lys(DNP)-Pro-OH
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Fórmula empírica (Notação de Hill):
C39H49N11O10 · xC2HF3O2
Peso molecular:
831.87 (free base basis)
Código UNSPSC:
12352200
NACRES:
NA.77
Produtos recomendados
![N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly](/deepweb/assets/sigmaaldrich/product/structures/225/349/530bc714-b1a8-4fdb-8082-a39329ee730a/640/530bc714-b1a8-4fdb-8082-a39329ee730a.png)
Ensaio
≥95% (HPLC)
forma
film
cor
yellow
temperatura de armazenamento
2-8°C
Amino Acid Sequence
Abz-Phe-Arg-Lys-DNP-Pro
Aplicação
Abz-FRK(Dnp)P-OH trifluoroacetate (TFA) is a substrate for the Angiotensin Converting Enzyme (ACE). Abz-FRK(Dnp)P-OH TFA has been used to study both the reduction of mortality of patients with sepsis and paracetamol-induced hypothermia.
Ações bioquímicas/fisiológicas
Substrate for ACE (Angiotensin Converting Enzyme). Internally quenched fluorogenic substrate for Real Time Fluorescent Assay.
Características e benefícios
This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Jérémie Neasta et al.
British journal of pharmacology, 173(8), 1314-1328 (2016-03-31)
Using an in-house bioinformatics programme, we identified and synthesized a novel nonapeptide, H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Here, we have studied its biological activity, in vitro and in vivo, and have identified its target in the brain. The affinity of the peptide was characterized
Maria Fernanda de M Costa et al.
Journal of veterinary science, 12(1), 21-25 (2011-03-04)
Angiotensin-I converting enzyme (ACE) is a key regulator of blood pressure, electrolytes and fluid homeostasis through conversion of angiotensin I into angiotensin II. Recently, a genetic polymorphism of the ACE gene, which accounts for 47% of the variation of ACE
Arnau Hervera et al.
Molecular pain, 7, 25-25 (2011-04-14)
The local administration of μ-opioid receptor (MOR) agonists attenuates neuropathic pain but the precise mechanism implicated in this effect is not completely elucidated. We investigated if nitric oxide synthesized by neuronal (NOS1) or inducible (NOS2) nitric oxide synthases could modulate
Samir S Ayoub et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(9), 1689-1695 (2011-06-02)
In recent years, there has been increasing interest in hypothermia induced by paracetamol for therapeutic purposes, which, in some instances, has been reported as a side effect. Understanding the mechanism by which paracetamol induces hypothermia is therefore an important question.
Wen Yang et al.
The Journal of pharmacology and experimental therapeutics, 339(3), 832-841 (2011-08-30)
Treatment with statins, inhibitors of HMG-CoA reductase, extends the survival of septic mice. However, the molecular mechanisms underlying the cholesterol-lowering, independent beneficial effects of statins in sepsis are poorly understood. The inhibition of protein isoprenylation, namely farnesylation and geranylgeranylation, has
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica