A211180

DMT-2′O-Methyl-rA(bz) Phosphoramidite

configured for PerkinElmer, configured for Polygen

• Sinônimo(s): DMT-2′-O-Me-rA(bz) amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-adenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Fórmula empírica (Notação de Hill): C₄₈H₅₄N₇O₈P
• Número CAS: 110782-31-5
• Peso molecular: 887.96
• Número MDL: MFCD00792622
• Código UNSPSC: 41116105
• ID de substância PubChem: 329770745
• NACRES: NA.51

Propriedades

• fonte biológica: non-animal source (no BSE/TSE risk)
• Nível de qualidade: 300
• linha de produto: Proligo Reagents
• Ensaio: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• forma: powder
• técnica(s): oligo synthesis: suitable
• Impurezas: ≤0.1% single unspecified Impurity (reversed phase HPLC); ≤0.3% mA2 (reversed phase HPLC, Hydrolysate); ≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me); ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT); ≤3% residual Solvent content
• cor: white to off-white
• λ: conforms (UV/VIS Identity)
• adequação: conforms to structure for H-NMR; conforms to structure for LC-MS
• compatibilidade: configured for PerkinElmer; configured for Polygen
• perfil de nucleosídeo: base: adenosine; base protecting group: benzoyl; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: standard
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6c(NC(=O)c7ccccc7)ncnc56
• InChI: 1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1
• chave InChI: AZCGOTUYEPXHMJ-PSVHYZMASA-N

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable