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Documentos Principais

A1131

Sigma-Aldrich

L-Anserine nitrate salt

≥98%

Sinônimo(s):

β-Ala-3-methyl-His nitrate salt, β-Alanyl-3-methyl-L-histidine nitrate salt

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About This Item

Fórmula empírica (Notação de Hill):
C10H16N4O3 · HNO3
Número CAS:
Peso molecular:
303.27
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.26

Nome do produto

L-Anserine nitrate salt, hydroxyl radical scavenger

Nível de qualidade

Ensaio

≥98%

Formulário

powder

cor

white

aplicação(ões)

detection

cadeia de caracteres SMILES

O[N+]([O-])=O.Cn1cncc1C[C@H](NC(=O)CCN)C(O)=O

InChI

1S/C10H16N4O3.HNO3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11;2-1(3)4/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17);(H,2,3,4)/t8-;/m0./s1

chave InChI

OLWOKAYJAHHSNY-QRPNPIFTSA-N

Ações bioquímicas/fisiológicas

L-Anserine s a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. It inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars. It is much less potent than L-carnosine as an inhibitor of protein-protein crosslinking.

Ligação

Anserine is a naturally occurring methylated analog of carnosine.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Daiki Kubomura et al.
Nutritional neuroscience, 13(4), 183-188 (2010-07-31)
Anserine and L-carnosine are similar dipeptides synthesized by muscles of vertebrates. The functional role of anserine is unknown, although previous studies showed hypoglycemic effects of carnosine through autonomic nerves. Thus, we evaluated the effects of anserine on blood glucose levels
Angelo Zinellu et al.
Talanta, 84(3), 931-935 (2011-04-13)
A field amplified sample injection (FASI) capillary electrophoresis method with UV detection was developed for the separation and detection of carnosine-related peptides carnosine (Car), anserine (Ans) and homocarnosine (Hcar). The imidazole dipeptides were baseline-separated within 10 min by using 50
Verena Peters et al.
Amino acids, 42(6), 2411-2416 (2011-08-13)
Recently, we identified an allelic variant of human carnosinase 1 (CN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in humans. Investigations in diabetic (db/db) mice showed that carnosine ameliorates glucose metabolism effectively. We
Wieslaw Kopec et al.
Antioxidants (Basel, Switzerland), 9(11) (2020-11-12)
The objective of the study was to test the effect of diets supplemented with β-alanine, L-histidine, and carnosine on the histidine dipeptide content and the antioxidative status of chicken breast muscles and blood. One-day-old Hubbard Flex male chickens were assigned
Milton Helfenstein et al.
Revista brasileira de reumatologia, 50(3), 313-327 (2010-12-03)
Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB) has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous medial knee pain with tenderness in

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