94261

LL-37 (human) trifluoroacetate salt

≥95% (HPLC)

• Sinônimo(s): Human LL-37 amide Trifluoroacetate
• Fórmula empírica (Notação de Hill): C₂₀₅H₃₄₁N₆₁O₅₂ · xC₂HF₃O₂
• Peso molecular: 4492.28 (free base basis)
• Código UNSPSC: 51101500
• NACRES: NA.85

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: powder (Lyophilisate)
• cor: colorless to white
• solubilidade: H₂O: 1 mg/mL, clear, colorless
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria; viruses
• Modo de ação: cell membrane | interferes
• temperatura de armazenamento: −20°C

Descrição

Amino Acid Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH₂

Descrição geral

Chemical structure: peptide

Aplicação

LL-37 is used to study host defense mechanisms.

Ações bioquímicas/fisiológicas

LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.

Embalagem

1mg

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)