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41525

Sigma-Aldrich

N,N-Dimethyl-6-propionyl-2-naphthylamine

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Sinônimo(s):

2-(Dimethylamino)-6-propionylnaphthalene, 6-Propionyl-2-(dimethylamino)naphthalene, Prodan

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About This Item

Fórmula empírica (Notação de Hill):
C15H17NO
Número CAS:
70504-01-7
Peso molecular:
227.30
Beilstein:
2723587
Número MDL:
MFCD00056615
Código UNSPSC:
12352116
ID de substância PubChem:
57650063
NACRES:
NA.32

linha de produto

BioReagent

Ensaio

≥98.0% (HPLC)

forma

solid

pf

137 °C (lit.)

solubilidade

DMF: soluble
acetone: soluble
acetonitrile: soluble
methanol: soluble

fluorescência

λex 361 nm; λem 498 nm in methanol

adequação

suitable for fluorescence

cadeia de caracteres SMILES

CCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3

chave InChI

MPPQGYCZBNURDG-UHFFFAOYSA-N

Categorias relacionadas

Aplicação

N,N-Dimethyl-6-propionyl-2-naphthylamine (Prodan), a membrane surface probe, may be used as a fluorescence probe in non-cell based in vitro assay for the determination of drug-phospholipid complex formation and to study membrane surface properties.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

Fluorescence of spectrin-bound Prodan

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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Nile Red BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

Sigma-Aldrich

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Justyna Barucha-Kraszewska et al.
Biochimica et biophysica acta, 1798(9), 1724-1734 (2010-06-01)
Fluorescence methods are widely used in studies of biological and model membranes. The dynamics of membrane fluorescent markers in their ground and excited electronic states and correlations with their molecular surrounding within the fully hydrated phospholipid bilayer are still not
Masaki Goto et al.
Langmuir : the ACS journal of surfaces and colloids, 26(16), 13377-13384 (2010-08-11)
The bilayer phase behavior of diheptadecanoylphosphatidylcholine (C17PC) with different vesicle sizes (large multilamellar vesicle (LMV) and giant multilamellar vesicle (GMV)) was investigated by fluorescence spectroscopy using a polarity-sensitive fluorescent probe Prodan under atmospheric and high pressures. The difference in phase
E K Krasnowska et al.
Biochimica et biophysica acta, 1511(2), 330-340 (2001-04-05)
The fluorescent membrane probe 6-propionyl-2-dimethylaminonaphthalene (Prodan) displays a high sensitivity to the polarity and packing properties of lipid membrane. Contrary to 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), Prodan can also monitor the properties of the membrane surface, i.e., the polar-head pretransition. In bilayers composed
E K Krasnowska et al.
Biophysical journal, 74(4), 1984-1993 (1998-04-17)
Fluorescence spectral features of 6-propionyl-2-dimethylaminonaphthalene (Prodan) in phospholipid vesicles of different phase states are investigated. Like the spectra of 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), the steady-state excitation and emission spectra of Prodan are sensitive to the polarity of the environment, showing a relevant
Renata K Everett et al.
The journal of physical chemistry. A, 114(14), 4946-4950 (2010-03-25)
The synthesis and photophysical properties of 7-(dimethylamino)-3,4-dihydrophenanthren-1(2H)-one (7) and 3-(dimethylamino)-8,9,10,11-tetrahydro-7H-cyclohepta[a]naphthalen-7-one (8) are reported. These compounds possess a cycloalkanone substructure that controls the extent of twisting of the carbonyl group. The six-membered ring in 7 forces the carbonyl group to be
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