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Merck
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Key Documents

342M-1

Sigma-Aldrich

Tryptase (G3) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

diluted ascites fluid

tipo de produto de anticorpo

primary antibodies

clone

G3, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

forma

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (342M-14)
vial of 0.5 mL concentrate (342M-15)
bottle of 1.0 mL predilute (342M-17)
vial of 1.0 mL concentrate (342M-16)
bottle of 7.0 mL predilute (342M-18)

fabricante/nome comercial

Cell Marque™

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1000

Isotipo

IgG1

controle

uterus

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... TPSAB1(7177)

Descrição geral

Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules and basophils. Upon cellular activation, these enzymes are released into the extracellular environment. Anti-tryptase is a good marker for mast cells, basophils, and their derivatives.

Qualidade


IVD
IVD
IVD
RUO

Ligação

Tryptase Positive Control Slides, Product No. 342S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Andreas Chott et al.
The American journal of surgical pathology, 27(7), 1013-1019 (2003-06-27)
Mast cell sarcoma is an extremely rare and aggressive type of mast cell disease. Only a few cases have been described so far, and little is known about the biology and phenotype of afflicted cells. We describe morphologic and immunophenotypic
J H Jordan et al.
Human pathology, 32(5), 545-552 (2001-06-19)
In an attempt to identify novel diagnostic markers for mast cell (MC)-proliferative disorders, serial bone marrow (bm) sections of 22 patients with mastocytosis (systemic indolent mastocytosis, n = 19; mast cell leukemia [MCL], n = 1; isolated bm mastocytosis, n
L Fiorucci et al.
Cellular and molecular life sciences : CMLS, 61(11), 1278-1295 (2004-06-02)
Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules of all mammalian organisms. These enzymes are released along with other mediators into the extracellular medium upon mast cell activation/degranulation. Among the trypsin-like enzymes, tryptases are
I S Roberts et al.
Journal of clinical pathology, 53(11), 858-862 (2000-12-29)
Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory
C Y Li
Leukemia research, 25(7), 537-541 (2001-05-30)
The diagnosis of mastocytosis or mast cell disease may be difficult sometimes because of the wide variety of clinical presentation, abnormal morphology of mast cells, and variation in histologic features which may mimic varieties of other diseases. Over the years
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