06892

(+)-Lariciresinol

≥95.0% (HPLC)

• Sinônimo(s): (2S,3R,4R)-Tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-furanmethanol, 4-[(2S,3R,4R)-4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]-2-methoxyphenol, NSC 329247
• Fórmula empírica (Notação de Hill): C₂₀H₂₄O₆
• Número CAS: 27003-73-2
• Peso molecular: 360.40
• Beilstein: 4560057
• Número MDL: MFCD07784476
• Código UNSPSC: 12352005
• ID de substância PubChem: 329748296
• NACRES: NA.25

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95.0% (HPLC)
• forma: powder
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• cadeia de caracteres SMILES: COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c3ccc(O)c(OC)c3)ccc1O
• InChI: 1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1
• chave InChI: MHXCIKYXNYCMHY-AUSJPIAWSA-N

Descrição

Descrição geral

Lariciresinol(LA) is a dietary phytoestrogen plant lignan. It is one of the main active phytochemicals in many traditional medicinal plants and cereals.

Aplicação

Lariciresinol has been used as a reference standard:

• in the purification, identification, and analysis of lignan phytoestrogens and lignan glycosides
• for the determination of the enantiomeric composition of lariciresinol from the pinoresinol to lariciresinol reduction reaction using high-performance liquid chromatography (HPLC)
• forqualitative and quantitative analysis of lignans in seven types of triticalegrain using ultra-performance liquid chromatography (UPLC)

Ações bioquímicas/fisiológicas

Lariciresinol is a potent dietary antioxidant and a radical scavenger by potentially chelating catalytic Fe²⁺ ions. It exerts antimicrobial effects against foodborne pathogens S. aureus and E. coli O157:H7. Lariciresinol is an effective anticancer agent that inhibits cell proliferation and induces apoptosis in human HepG2 cells in vitro. It also displays anti-inflammatory and anti-diabetic effects in vitro and in vivo studies respectively.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações de segurança

• Pictogramas: GHS09
• Palavra indicadora: Warning
• Frases de perigo: H400
• Declarações de precaução: P273 - P391 - P501
• Classificações de perigo: Aquatic Acute 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable