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Documentos Principais

Y0001462

Acetylsulfadiazine

European Pharmacopoeia (EP) Reference Standard

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About This Item

Fórmula empírica (Notação de Hill):
C12H12N4O3S
Número CAS:
Peso molecular:
292.31
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

sulfadiazine

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[S](=O)(=O)(Nc2ncccn2)c1ccc(cc1)NC(=O)C

InChI

1S/C12H12N4O3S/c1-9(17)15-10-3-5-11(6-4-10)20(18,19)16-12-13-7-2-8-14-12/h2-8H,1H3,(H,15,17)(H,13,14,16)

chave InChI

NJIZUWGMNCUKGU-UHFFFAOYSA-N

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Acetylsulfadiazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

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Christiane Zarfl et al.
Chemosphere, 77(6), 720-726 (2009-09-22)
Sulfadiazine (SDZ) belongs to the chemical class of sulfonamides, one of the most important groups of antibiotics applied in animal husbandry in Europe. These antibiotics end up in the soil after manure from treated animals is applied as fertilizer. They
T Bergan et al.
Chemotherapy, 32(6), 478-485 (1986-01-01)
The study was aimed at analyzing the pharmacokinetics of sulphadiazine (SDZ) and trimethoprim (TMP) in geriatric patients and was carried out in two stages. The first stage compared 11 geriatric patients (68-89 years old) and 9 healthy volunteers (21-34 years
Sulfadiazine/N4-acetylsulfadiazine crystalluria in a patient with the acquired immune deficiency syndrome (AIDS)
J L Potter et al.
Clinica chimica acta; international journal of clinical chemistry, 230(2), 221-224 (1994-10-31)
G C Batzias et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 769(2), 253-259 (2002-05-09)
A new method for simultaneous quantification of trimethoprim, sulfadiazine and N4-acetylsulfadiazine in plasma of broilers at levels down to 13-16 ng/ml has been developed. Samples were deproteinized with acetonitrile, defatted with hexane, and extracted with dichloromethane. Chromatographic analysis was carried
Turner's syndrome with anorexia nervosa.
T Ohzeki et al.
The American journal of medicine, 84(4), 792-793 (1988-04-01)

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