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Key Documents

PHR1520

Supelco

Chlortetracycline Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Chlortetracycline hydrochloride, 7-Chlorotetracycline hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C22H23ClN2O8 · HCl
Número CAS:
Peso molecular:
515.34
Beilstein:
3858364
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to BP 783
traceable to Ph. Eur. C2000000
traceable to USP 1129007

família API

chlortetracycline

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 500 mg

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

210-215 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

-10 to -25°C

cadeia de caracteres SMILES

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

chave InChI

CBHYYLPALVVVEY-LYNLVHCPSA-N

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Descrição geral

Chlortetracycline Hydrochloride is a salt of chlortetracycline, which is a tetracycline which shows broad-spectrum antibiotic activity. It is generally used as a veterinary and aquaculture medicine. It is often used on dairy cattle and aquacultured catfish, salmon, and lobster.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Chlortetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC3430 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

Health hazardExclamation mark

Palavra indicadora

Warning

Classificações de perigo

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Determination of tetracycline residues in shrimp and whole milk using liquid chromatography with ultraviolet detection and residue confirmation by mass spectrometry
Andersen WC, et al.
Analytica Chimica Acta, 529(1-2), 145-150 (2005)
The spectrophotometric assay for chlortetracycline HCl and tetracycline HCl in pharmaceuticals
Chiccarelli FS, et al.
Journal of the American Pharmaceutical Association, 48(5), 263-268 (1959)

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