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Key Documents

Y0001242

Folic acid impurity A

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

N-(4-Aminobenzoyl)-L-glutamic acid

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About This Item

Fórmula empírica (Notação de Hill):
C12H14N2O5
Número CAS:
Peso molecular:
266.25
Beilstein:
2816320
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

folic acid

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1

chave InChI

GADGMZDHLQLZRI-VIFPVBQESA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Folic acid impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Lot/Batch Number

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Pteroic acid ≥93%

Sigma-Aldrich

P1781

Pteroic acid

Biotina European Pharmacopoeia (EP) Reference Standard

Y0001978

Biotina

L-cistina European Pharmacopoeia (EP) Reference Standard

C3300000

L-cistina

Sacarose European Pharmacopoeia (EP) Reference Standard

S1600000

Sacarose

M Laura Dántola et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(12), 1604-1612 (2010-10-06)
Folic acid, or pteroyl-l-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a glutamic acid (Glu)
Guifeng Li et al.
The journal of physical chemistry. B, 116(10), 3467-3475 (2012-03-01)
Conformational control of excited-state intramolecular electron transfer (ET) in folic acid (FA) has been investigated using femtosecond time-resolved infrared (TRIR) spectroscopy. Ultrafast excited-state ET between the pterin and the 4-aminobenzoyl subunits of FA is observed for the anionic form (at
A A H Sokoro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 832(1), 9-16 (2006-01-24)
To develop a routine method for quantitative measurement of the folate catabolites p-aminobenzoylglutamate (pABG) and acetamidobenzoylglutamate (apABG) in serum and urine using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Urine, serum and aqueous standards were thawed. Two microliters of d3-glutamic acid (d3-Glu;
Yumei Lin et al.
The American journal of clinical nutrition, 80(3), 680-691 (2004-08-24)
A quantitative understanding of human folate metabolism is needed. The objective was to quantify and interpret human folate metabolism as it might occur in vivo. Adults (n = 13) received 0.5 nmol [(14)C]pteroylmonoglutamate (100 nCi radioactivity) plus 79.5 nmol pteroylmonoglutamate
Vellappan Kesavan et al.
Journal of radiation research, 44(2), 141-144 (2003-09-19)
Concentrations of total folates and their oxidative degradate, para-aminobenzoyl glutamic acid, were determined in mouse after 2-7 Gy total body gamma-irradiation (TBI). Total liver folate levels were drastically reduced by almost 47% over a period of 120 h after TBI

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