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Key Documents

F0300000

Ácido fólico

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

PteGlu, Vitamina M, Ácido pteroil-L-glutâmico

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About This Item

Fórmula empírica (Notação de Hill):
C19H19N7O6
Número CAS:
Peso molecular:
441.40
Beilstein:
100781
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

fonte biológica

synthetic

grau

pharmaceutical primary standard

família API

folic acid

forma

solid

fabricante/nome comercial

EDQM

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

pf

>285 °C

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

chave InChI

OVBPIULPVIDEAO-LBPRGKRZSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Folic acid, a water-soluble B vitamin, is available in several food products. As it is not generated in the human body, diet is one of the easiest ways to obtain it. It plays a crucial role in the biochemical synthesis and repair of DNA and is used in the management of megaloblastic anemias, neural tube defects such as anencephaly and spina bifida. Pharmaceutical drug forms of folic acid are desirable for supplementing its consumption through the diet.

Aplicação

Folic acid may be used as an European Pharmacopoeia reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1


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European pharmacopoeia, 6(5-6), 5662-5663 (2018)
Adsorptive stripping voltammetric determination of folic acid in pharmaceutical preparations
Szczepaniak W and Ren M
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Determination of folic acid in tablets by microemulsion electrokinetic chromatography
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Flow injection chemiluminometric determination of folic acid in pharmaceutical formulations
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Analytical Sciences, 10(6), 919-922 (1994)

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