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Y0000398

Methyl nicotinate

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Nicotinic acid methyl ester

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About This Item

Fórmula empírica (Notação de Hill):
C7H7NO2
Número CAS:
93-60-7
Peso molecular:
137.14
Beilstein:
113951
Número MDL:
MFCD00006388
Código UNSPSC:
41116107
ID de substância PubChem:
329830933
NACRES:
NA.24

fonte biológica

synthetic

grau

pharmaceutical primary standard

Agency

EP

família API

methyl nicotinate

Formulário

solid

fabricante/nome comercial

EDQM

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

p.e.

204 °C (lit.)

pf

42-44 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

COC(=O)c1cccnc1

InChI

1S/C7H7NO2/c1-10-7(9)6-3-2-4-8-5-6/h2-5H,1H3

chave InChI

YNBADRVTZLEFNH-UHFFFAOYSA-N

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Descrição geral

Methyl nicotinate is a potent vasodilatory drug capable of transdermal penetration. It is known to elicit distinctive erythema through the production of prostaglandin D2(PGD2) and beneficial for the treatment of respiratory, vascular and rheumatoid disorders.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Methyl nicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

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Preços

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

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Lot/Batch Number

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Delayed vasodilatory response to methylnicotinate in patients with unipolar depressive disorder
Ross BM, et al.
Journal of Affective Disorders, 82(2), 285-290 (2004)
Identification and quantification of methyl nicotinate in rice (Oryza sativa L.) by gas chromatography-mass spectrometry
RB Muralidhara, et al.
Food Chemistry, 105(2), 736-741 (2007)
Penny N Newson et al.
Behavioural brain research, 272, 55-65 (2014-07-01)
Treatment of neonatal rats with the transient receptor potential vanilloid 1 (TRPV1) channel agonist, capsaicin, produces life-long loss of sensory neurons expressing TRPV1 channels. Previously it was shown that rats treated on day 2 of life with capsaicin had behavioural
Stéphanie Romand et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63, 14-21 (2014-07-06)
A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated capillary in aqueous medium and

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