X4251

XTT sodium salt

analytical standard, ≥90%

• Sinônimo(s): 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
• Fórmula empírica (Notação de Hill): C₂₂H₁₆N₇NaO₁₃S₂
• Número CAS: 111072-31-2
• Peso molecular: 673.52
• Número MDL: MFCD00083517
• Código UNSPSC: 41116107
• ID de substância PubChem: 329830806
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Ensaio: ≥90%
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O
• InChI: 1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
• chave InChI: JACYMBNQPPWQML-UHFFFAOYSA-M

Descrição

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Useful in AIDS and cancer testing.

XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.

Princípio

In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

Informações de segurança

• Pictogramas: GHS02
• Palavra indicadora: Danger
• Frases de perigo: H242
• Declarações de precaução: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classificações de perigo: Self-react. C
• Perigos de suplementos: EUH044
• Código de classe de armazenamento: 4.1A - Other explosive hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)