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S6814

Sigma-Aldrich

SynaptoGreen™ C4

≥95% (HPLC), solid

Sinônimo(s):

FM1-43, N-(3-triethylammoniumpropyl) -4-(4-(dibutylamino)styryl) pyridinium dibromide, Pyridinium, 4-[2-[4-(dibutylamino)phenyl]ethenyl]- 1-[3-(triethylammonio)propyl]- , dibromide

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About This Item

Fórmula empírica (Notação de Hill):
C30H49Br2N3
Número CAS:
149838-22-2
Peso molecular:
611.54
Número MDL:
MFCD00467815
Código UNSPSC:
12171500
ID de substância PubChem:
329824569
NACRES:
NA.47

Nível de qualidade

100

Ensaio

≥95% (HPLC)

forma

solid

cor

dark red

solubilidade

DMSO: soluble
H2O: soluble

εmax

≥50000 at 507-513 nm in methanol

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[Br-].[Br-].CCCCN(CCCC)c1ccc(\C=C\c2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1

InChI

1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5;;/h14-21,25-26H,6-13,22-24,27H2,1-5H3;2*1H/q+2;;/p-2

chave InChI

VZUVCAGXYLMFEC-UHFFFAOYSA-L

Categorias relacionadas

Descrição geral

SynaptoGreen™ C4 is an oxonol dye that helps in the rapid detection of an antibiotic′s effect on bacterial viability. It is a fluorescent dye that is used in optical imaging studies to determine synaptic activity by staining synaptic vesicles at the nerve terminal or the neuromuscular junction. It is equivalent to FM1-43.

Aplicação

SynaptoGreen™ C4 has been used to label cultured neurons grown on EM grids for fluorescent labeling, live light microscopy and imaging studies.

Ações bioquímicas/fisiológicas

A fluorescent nerve terminal dye suitable for monitoring synaptic activity at synapses and at neuromuscular junctions.

Outras notas

Component of NTSI, also sold individually.

Informações legais

SynaptoGreen is a trademark of Biotium, Inc.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCQ0878
MKCK9991
MKCK5858
MKCK3521
MKCJ5448

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Yalda Moayedi et al.
Scientific reports, 8(1), 9975-9975 (2018-07-04)
Oral mechanoreception is implicated in fundamental functions including speech, food intake and swallowing; yet, the neuroanatomical substrates that encode mechanical stimuli are not well understood. Tactile perception is initiated by intricate mechanosensitive machinery involving dedicated cells and neurons. This signal
Yangbin Gao et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(7), 2275-2280 (2015-02-04)
Auxin binding protein 1 (ABP1) has been studied for decades. It has been suggested that ABP1 functions as an auxin receptor and has an essential role in many developmental processes. Here we present our unexpected findings that ABP1 is neither
Tam H Nguyen et al.
PloS one, 7(5), e36913-e36913 (2012-05-26)
Bulk endocytosis contributes to the maintenance of neurotransmission at the amphibian neuromuscular junction by regenerating synaptic vesicles. How nerve terminals internalize adequate portions of the presynaptic membrane when bulk endocytosis is initiated before the end of a sustained stimulation is
Christopher R Heier et al.
EMBO molecular medicine, 5(10), 1569-1585 (2013-09-10)
Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain
Roman Pleskot et al.
Frontiers in plant science, 3, 54-54 (2012-05-29)
Phosphatidic acid (PA) is an important intermediate in membrane lipid metabolism that acts as a key component of signaling networks, regulating the spatio-temporal dynamics of the endomembrane system and the cytoskeleton. Using tobacco pollen tubes as a model, we addressed
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