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RDD039

Sigma-Aldrich

Imidazol

for molecular biology, ≥99% (titration), free-flowing, Redi-Dri™

Sinônimo(s):

1,3-Diaza-2,4-ciclopentadieno, Glioxalina

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About This Item

Fórmula empírica (Notação de Hill):
C3H4N2
Número CAS:
288-32-4
Peso molecular:
68.08
Beilstein:
103853
Número MDL:
MFCD00005183
Código UNSPSC:
12352200
NACRES:
NA.21

grau

for molecular biology

Nível de qualidade

100

pressão de vapor

<1 mmHg ( 20 °C)

linha de produto

Redi-Dri™

Ensaio

≥99% (titration)

Formulário

crystalline powder

qualidade

free-flowing

pH

6.2-7.8 (25 °C)

pKa (25 °C)

6.95

p.e.

256 °C (lit.)

pf

88-91 °C (lit.)

aplicação(ões)

diagnostic assay manufacturing

atividade externa

DNase, RNase and protease, none detected

cadeia de caracteres SMILES

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

chave InChI

RAXXELZNTBOGNW-UHFFFAOYSA-N

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Descrição geral

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar.

Aplicação

Imidazole has been used
  • in the lysis, wash, and elution buffer for the purification of histidine tagged proteins
  • in gradient for the purification of histidine tagged proteins using nickel affinity chromatography
  • as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells
Excelente para tampões na faixa de pH de 6,2-7,8

Ações bioquímicas/fisiológicas

Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).

Características e benefícios

  • Qualified for molecular biology applications, DNase, Rnase, and protease free
  • Redi-Dri™ packaging controls moisture, eliminating clumps
  • Crystalline powder remains free-flowing and much easier to use
  • Safer to handle and weigh out for routine use in lab
  • Less waste, loss of drying, while maintaining high quality

Outras notas

For additional information on our range of Biochemicals, please complete this form.

Informações legais

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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Palavra indicadora

Danger

Frases de perigo

H302,H314,H360D

Classificações de perigo

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

293.0 °F - closed cup

Ponto de fulgor (°C)

145 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number
SLCG7433

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