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Key Documents

C4255

Sigma-Aldrich

Creatinine

anhydrous, ≥98%

Sinônimo(s):

2-Amino-1-methyl-2-imidazolin-4-one, 2-Imino-1-methylimidazolidin-4-one, 2-Imino-N-methylhydantoin

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About This Item

Fórmula empírica (Notação de Hill):
C4H7N3O
Número CAS:
Peso molecular:
113.12
Beilstein:
112061
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

grau

anhydrous

Nível de qualidade

Ensaio

≥98%

forma

powder

pf

295 °C (dec.) (lit.)

cadeia de caracteres SMILES

CN1CC(=O)N=C1N

InChI

1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

chave InChI

DDRJAANPRJIHGJ-UHFFFAOYSA-N

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Descrição geral

Creatinine is a breakdown product formed by the degradation of creatine phosphate from muscles. The kidneys extract creatinine from the body by filtering almost all of it from the blood and excreting it in the urine. Serum creatinine is the most commonly used indicator for renal functioning. In chemical synthesis, creatinine is used as a heterocyclic nitrogenous compound that produces electron-rich and highly basic creatinine derivatives.

Aplicação

Creatinine can be used as:
  • A nitrogen donor building block to prepare nitrogen-containing heterocyclic derivatives.
  • A reactant to synthesize donor-acceptor type carbon nitride copolymer, which is used as a photocatalyst in hydrogen production.
  • A starting material to prepare creatol(2-amino-1,5-dihydro-5-hydroxy methylimidazol-4-one) via creatinine chloramine.
  • A reactant to synthesize 3-substituted-3-hydroxyisatins by gold-catalyzed aldolization with various isatins.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

554.0 °F - closed cup

Ponto de fulgor (°C)

290 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Study of Creatinine and its 5-Alkoxy Analogs: Structure and Conformational Studies in the Solid and Solution States by X-Ray Crystallography, NMR, UV and Mass Spectrometry
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Nucleosides, nucleotides & nucleic acids, 16(12), 2193-2218 (1997)
A Simple Conversion of Creatinine to Creatol via Creatinine Chloroamine
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In this multicenter, open-label, randomized controlled trial, we determined whether 2-month prednisolone therapy for steroid-sensitive nephrotic syndrome was inferior or not to 6-month therapy despite significantly less steroid exposure. The primary end point was time from start of initial treatment

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