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60634

Sigma-Aldrich

Catalase from Micrococcus lysodeikticus

solution, dark brown

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.54

fonte biológica

bacterial (Micrococcus lysodeikticus)

Nível de qualidade

Formulário

solution

atividade específica

65,000-150,000 U/mL

peso molecular

Mr ~230000

técnica(s)

microbe id | metabolite detection: suitable

cor

dark brown

solubilidade

0.05 M phosphate buffer pH 7.0: soluble, clear, brown (1:10)

nº de adesão de ID de proteína

nº de adesão UniProt

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

chave InChI

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Descrição geral

Research area: Cell Signaling

Catalase (CAT) is an antioxidant enzyme, encoded by the CAT gene family. The enzyme is ubiquitously expressed in most of the aerobic organisms.

Aplicação

Catalase from Micrococcus lysodeikticus has been used to eliminate excess of hydrogen peroxide production during sugar analog synthesis by in vitro biocatalytic cascade. It has also been used as a standard to evaluate oxidative stress by indirectly measuring catalytic activity.

Ações bioquímicas/fisiológicas

Catalase rapidly converts hydrogen peroxide to oxygen and water. It exhibits antioxidant activity and elicits a defense mechanism against reactive oxygen species (ROS). Catalase plays a role in neutralizing noxious hydrogen peroxide in nature as well as in various industries such as textile, pharma, and dairy. Micrococcus lysodeikticus catalase is a heme-containing protein.Catalase, along with various key cellular systems involved in hydrogen peroxide (H2O2) processing, plays a key role in regulating cellular redox balance and aids in cellular and intercellular signaling.

Definição da unidade

1 U corresponds to the amount of enzyme which decomposes 1 μmol H2O2 per minute at pH 7.0 and 25 °C

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Resp. Sens. 1

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves


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Hessam Sepasi Tehrani et al.
Progress in biophysics and molecular biology, 140, 5-12 (2018-03-14)
Catalase is one of the firsts in every realm of biological sciences. At the same time it also has a number of unusual features. It has one of the highest turnover numbers of all enzymes. It is essential for neutralizing
Pablo Burraco et al.
BMC evolutionary biology, 17(1), 164-164 (2017-07-08)
Adaptive plasticity is essential for many species to cope with environmental heterogeneity. In particular, developmental plasticity allows organisms with complex life cycles to adaptively adjust the timing of ontogenetic switch points. Size at and time to metamorphosis are reliable fitness
Ivan Gomez-Mestre et al.
PloS one, 8(12), e84266-e84266 (2013-12-21)
Many amphibian species exploit temporary or even ephemeral aquatic habitats for reproduction by maximising larval growth under benign conditions but accelerating development to rapidly undergo metamorphosis when at risk of desiccation from pond drying. Here we determine mechanisms enabling developmental
Margarita Florencio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 242, 110654-110654 (2020-01-12)
Organisms are exposed to multiple environmental factors simultaneously to which they often respond behaviorally, morphologically and/or physiologically. Amphibian larvae are quite plastic and efficiently adjust their phenotype and physiology to the reigning local conditions. Here we tested whether the combination
An improved procedure using ferricyanide for detecting catalase isozymes.
W Woodbury et al.
Analytical biochemistry, 44(1), 301-305 (1971-11-01)

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