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Key Documents

44179

Supelco

Morphine sulfate salt pentahydrate

analytical standard

Sinônimo(s):

Morphine hemi[sulfate pentahydrate]

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About This Item

Fórmula empírica (Notação de Hill):
C34H40N2O10S · 5H2O
Número CAS:
Peso molecular:
758.83
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Ensaio

≥98.5% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

controle de medicamentos

USDEA Schedule II; Home Office Schedule 2; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O.O.O.O.O.OS(O)(=O)=O.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35.CN6CC[C@]78[C@H]9Oc%10c(O)ccc(C[C@@H]6[C@@H]7C=C[C@@H]9O)c8%10

InChI

1S/2C17H19NO3.H2O4S.5H2O/c2*1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4;;;;;/h2*2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4);5*1H2/t2*10-,11+,13-,16-,17-;;;;;;/m00....../s1

chave InChI

GRVOTVYEFDAHCL-RTSZDRIGSA-N

Informações sobre genes

human ... OPRM1(4988)

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Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Kirsten M Raehal et al.
Drug and alcohol dependence, 104(3), 187-196 (2009-06-06)
G protein-coupled receptor kinases (GRKs) are a family of intracellular proteins that desensitize and regulate the responsiveness of G protein-coupled receptors (GPCRs). In the present study, we assessed the contribution of GRK6 to the regulation and responsiveness of the G
Shilong Yang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17534-17539 (2013-10-02)
Loss-of-function mutations in the human voltage-gated sodium channel NaV1.7 result in a congenital indifference to pain. Selective inhibitors of NaV1.7 are therefore likely to be powerful analgesics for treating a broad range of pain conditions. Herein we describe the identification
Lori N Eidson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(40), 15952-15963 (2013-10-04)
The ventrolateral periaqueductal gray (vlPAG) is an integral locus for morphine action. Although it is clear that glia contribute to the development of morphine tolerance, to date, the investigation of their role has been limited to spinal and medullary loci.
Virginia Aguado-Lorenzo et al.
Archives of disease in childhood, 98(12), 975-979 (2013-10-24)
To investigate the accuracy of morphine infusions prepared for neonates in relation to the label strength and to identify the differences in deviation between infusions made in neonatal intensive care unit (NICU) and those dispensed ready-to-use from pharmacy. Unused portions
Marsha A Raebel et al.
JAMA, 310(13), 1369-1376 (2013-10-03)
Obesity is associated with chronic noncancer pain. It is not known if opioid use for chronic pain in obese individuals undergoing bariatric surgery is reduced. To determine opioid use following bariatric surgery in patients using opioids chronically for pain control

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