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439223

Sigma-Aldrich

Diclorometano

suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer

Sinônimo(s):

Cloreto de metileno

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About This Item

Fórmula empírica (Notação de Hill):
CH2Cl2
Número CAS:
Peso molecular:
84.93
Beilstein:
1730800
Número CE:
Número MDL:
Código UNSPSC:
12190000
ID de substância PubChem:
NACRES:
NA.21

grau

HPLC grade

Nível de qualidade

densidade de vapor

2.9 (vs air)

pressão de vapor

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

Ensaio

≥99.9%

Formulário

liquid

temperatura de autoignição

1223 °F

contém

40-150 ppm amylene as stabilizer

Lim. expl.

22 %

técnica(s)

HPLC: suitable

Impurezas

Free halogens, passes test
≤0.0003 meq/g Titr. acid
≤0.02% water

resíduo de evaporação

<0.0003%

cor

APHA: ≤10
clear

índice de refração

n20/D 1.424 (lit.)

p.e.

39.8-40 °C (lit.)

pf

−95 °C (lit.)

densidade

1.325 g/mL at 25 °C (lit.)

λ

H2O reference

Absorção UV

λ: 235 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 250 nm Amax: 0.05
λ: 260 nm Amax: 0.02
λ: 340-400 nm Amax: 0.01

adequação

passes test for HPLC

cadeia de caracteres SMILES

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

chave InChI

YMWUJEATGCHHMB-UHFFFAOYSA-N

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Descrição geral

Dichloromethane (DCM) is a chlorinated organic solvent with a wide range of industrial applications. It has C2v symmetry, low boiling point, high density and is immiscible in water. Degradation of DCM by various methods has been reported. Ultrasonic absorption studies of liquid DCM shows strong relaxation effect. A study reports the dielectric characteristics of DCM over a wide frequency range. DCM is susceptible to degradation with time, which can be suppressed by adding amylene as a stabilizer.

Aplicação

Dichloromethane (Methylene chloride) may be used in the following processes:
  • To compose ultrasonic baths for cleaning and protection of aluminum coating over atactic-PMMA (poly(methyl methacrylate)) for dielectric studies.
  • Preparation of AMBF3 (ammoniomethyltrifluoroborate)-conjugated biomolecules.
  • Sample preparation for GC-MS (Gas Chromatography-Mass Spectrometry) analysis.
  • Preparation of ammonium acetate solvent mixture in combination with isopropanol, acetonitrile and water for mass spectral analysis of neutral lipids.
  • Quantification of glutathione (GSH) and glutathione disulfide (GSSG) in biological samples by HPLC and spectrophotometry.
  • As an extractant for 2,2-dithioethyl-4-(2′-pyridyl)-4-butyro-γ-lactone.
Meets ACS specifications

Embalagem

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Nota de preparo

Product filtered through a 0.2 μm filter

Pictogramas

Health hazardExclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

does not flash

Ponto de fulgor (°C)

does not flash

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves


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This protocol describes a procedure for determining glutathione (GSH) and glutathione disulfide (GSSG) concentrations in blood and other tissues. Artifactual oxidation to GSSG of 5-15% of the GSH found in a sample can occur during deproteination of biological samples with
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Methods in enzymology, 538, 89-105 (2014-02-18)
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Glucosinolates from the genus Brassica can be converted into bioactive compounds known to induce phase II enzymes, which may decrease the risk of cancers. Conversion via hydrolysis is usually by the brassica enzyme myrosinase, which can be inactivated by cooking
Vitamin B12-mediated hydrodechlorination of dichloromethane by bimetallic Cu/Al particles.
Huang CC, et al.
Chemical Engineering Journal, 273, 413-420 (2015)
Dichloromethane Detection Based on Near-Infrared Absorptive Sensing.
Han JH and Yoon SM
IEEE Journal of Selected Topics in Quantum Electronics, 18(5), 1547-1552 (2012)

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