410225

Glicina

≥98.5%, ACS reagent for peptide synthesis

• Sinônimo(s): Glicocol, Ácido aminoacético, Ácido aminoetanoico
• Fórmula linear: NH₂CH₂COOH
• Número CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de substância PubChem: 24865701
• NACRES: NA.21

Propriedades

• Nome do produto: Glicina, ACS reagent, ≥98.5%
• grau: ACS reagent
• Nível de qualidade: 200
• Ensaio: ≥98.5%
• Formulário: powder, crystals or granules
• Impurezas: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• resíduo de ignição: ≤0.1%
• cor: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• pf: 240 °C (dec.) (lit.)
• traços de ânion: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• traços de cátion: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• aplicação(ões): peptide synthesis
• grupo funcional: amine; carboxylic acid
• cadeia de caracteres SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• chave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informações sobre genes: rat ... Grin2a(24409)

Descrição

Descrição geral

Glycine is the simplest amino acid building block.

Aplicação

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Ações bioquímicas/fisiológicas

Neurotransmissor inibitório na coluna vertebral, regulador alostérico dos receptores de NMDA.

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)