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Merck
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Key Documents

23182

Supelco

(+)-1-(9-Fluorenyl)ethyl chloroformate solution

≥18 mM in acetone, for chiral derivatization, LiChropur

Sinônimo(s):

(+)-FLEC solution

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About This Item

Fórmula empírica (Notação de Hill):
C16H13ClO2
Número CAS:
Peso molecular:
272.73
Número MDL:
Código UNSPSC:
12000000
ID de substância PubChem:
NACRES:
NA.22

grau

for chiral derivatization

Nível de qualidade

linha de produto

ChiraSelect

pureza óptica

enantiomeric ratio: ≥99.0:1.0 (HPLC)

qualidade

LiChropur

concentração

≥18 mM in acetone

técnica(s)

HPLC: suitable

índice de refração

n20/D 1.359

temperatura de armazenamento

2-8°C

InChI

1S/C16H13ClO2/c1-10(19-16(17)18)15-13-8-4-2-6-11(13)12-7-3-5-9-14(12)15/h2-10,15H,1H3

chave InChI

SFRVOKMRHPQYGE-UHFFFAOYSA-N

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Descrição geral

(+)-1-(9-Fluorenyl)ethyl chloroformate [(+)-FLEC] is a chiral derivatizing reagent. It helps in separating enantiomers of α-amino acids, as well as helps in determining its optical purity using HPLC method.

Aplicação

(+)-FLEC may be used in enantioselective analysis of glufosinate using reversed-phase high-performance liquid chromatography system coupled with a fluorescence detection system.

forma física

solution, 5 mg in 1 mL acetone

Outras notas

Chiral derivatizing agent for primary and secondary amino acids and amines. The derivatives are separated by reversed-phase LC with fluorescence detection for determining the enantiomeric purity

Produtos recomendados

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informações legais

ChiraSelect is a trademark of Sigma-Aldrich Co. LLC
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

FlameExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Perigos de suplementos

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

1.4 °F

Ponto de fulgor (°C)

-17 °C


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Separation of enantiomers of a-hydroxy acids by reversed-phase liquid chromatography after derivatization with 1-(9-fluorenyl) ethyl chloroformate.
Fransson, Bengt, and Ulf Ragnarsson.
Journal of Chromatography A, 827, 31-36 (1998)
E Frigerio et al.
Journal of chromatography. A, 660(1-2), 351-358 (1994-02-04)
A sensitive and selective high-performance liquid chromatographic method for the determination of reboxetine enantiomers in human plasma was developed. Although two chiral centres are present in reboxetine, its stereospecific synthesis leads to two rather than four possible enantiomers. After extraction
Y Bergqvist et al.
Journal of chromatography, 652(1), 73-81 (1994-01-14)
A sensitive, stereoselective and rapid reversed-phase liquid chromatographic method for the determination of (SR)- and (RS)-mefloquine enantiomers in 100 microliters plasma and capillary blood collected on chromatographic paper is presented. The assay involves protein precipitation from plasma, liquid-liquid extraction of
K C Chan et al.
Electrophoresis, 16(4), 504-509 (1995-04-01)
Direct enantiomeric separations of some racemic amino acids derivatized with 9-fluorenylmethyl chloroformate were obtained using cyclodextrin-modified micellar electrokinetic chromatography (CD/MEKC) with a buffer made up of 5 mM sodium borate (pH 9.2), 150 mM sodium dodecyl sulfate (SDS) and 40
J Sukbuntherng et al.
Journal of analytical toxicology, 19(3), 139-147 (1995-05-01)
To study the disposition kinetics of methamphetamine (MAP), we have developed a sensitive high-performance liquid chromatographic (HPLC) assay to quantitate the enantiomers of MAP and its major metabolites, amphetamine (AP), p-hydroxymethamphetamine (p-OH-MAP), and p-hydroxyamphetamine (p-OH-AP), the latter two of which

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