MABT198

Anti-Connexin-26 Antibody, clone 3B12.1

clone 3B12.1, from mouse

• Sinônimo(s): Gap junction beta-2 protein, Connexin-26, Cx26
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100; 200
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 3B12.1, monoclonal
• reatividade de espécies: rat, human
• técnica(s): immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_003995
• nº de adesão UniProt: P29033
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GJB2(2706)

Descrição

Descrição geral

Connexin-2 is also known as Connexin Gap junction beta-2 protein (GJB2) and Connexin-26 (Cx26). The connexins are transmembrane channels that diffuse low MW materials from one cell to a neighboring cell. Aberrant connexin-2 can cause deafness autosomal recessive type 1A (DFNB1A), deafness autosomal dominant type 3A (DFNA3A), Vohwinkel syndrome (VS), palmoplantar keratoderma with deafness (PPKDFN), keratitis-ichthyosis-deafness syndrome (KID syndrome), Bart-Pumphrey syndrome (BPS), and ichthyosis hystrix-like with deafness syndrome (HID syndrome).

Especificidade

Other homologies: Mouse (92% sequence homology).

Imunogênio

KLH-conjugated linear peptide corresponding to human Connexin-26.

Aplicação

Anti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Connexin-26 in human colon and human liver tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Qualidade

Evaluated by Western Blotting in rat liver tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Connexin-26 in 10 µg of rat liver tissue lysate.

Descrição-alvo

~26 kDa observed

forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Rat liver tissue lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable