MABC971

Anti-Kallikrein-13/KLK13 Antibody, clone 33.1

clone 33.1, from mouse

• Sinônimo(s): Kallikrein-13, Kallikrein-like protein 4, KLK-L4
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 33.1, monoclonal
• reatividade de espécies: human
• técnica(s): ELISA: suitable; immunohistochemistry: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_056411
• nº de adesão UniProt: Q9UKR3
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KLK13(26085)

Descrição

Descrição geral

Kallikreins-related peptidases (KLKs) are proteases that are important for the desquamation process of the skin (cell shedding). Kallikreins are also associated with carcinogenesis and some serve as a novel cancer and other disease biomarkers. Kallikrein-13/KLK13 is important in lung cancer by allowing lung adenocarcinoma spreading through promoting the expression of various adhesion molecules and it in assisting in extracellular matrix protein degradation necessary for movement. Kallikrein-13/KLK13 also plays a role in salivary tumors and ovarian cancer as well as other cancers in a similar fashion. In both normal and cancerous tissues, Kallikrein-13/KLK13 is secreted into the ECM and expressed in many tissues in both the embryo and adult.

Imunogênio

Recombinant protein corresponding to Human Kallikrein-13/KLK13.

Aplicação

Immunohistochemistry Analysis: A representative lot of this antibody detected Kallikrein-13/KLK13 in Normal ovarian surface epithelium and epithelial ovarian cancer tissues (White et al., (2009) British Journal of Cancer. 101:1107-1113).

ELISA: A representative lot of this antibody detected various Kallikrein-13/KLK13 concentrations of several human tissues (Kapadia et al., (2003) Clinical chemistry. 49(1):77–86).

This Anti-Kallikrein-13/KLK13 Antibody, clone 33.1 is validated for use in Immunohistochemistry and ELISA for the detection of Kallikrein-13/KLK13.

Qualidade

Evaluated by Immunohistochemistry in human lung and human prostate tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Kallikrein-13/KLK13 in human prostate tissue.

Descrição-alvo

30 kDa calculated

forma física

Format: Purified

Purified mouse monoclonal IgG1k in 0.1 M Sodium Bicarbonate buffer pH8.2 without preservatives.

Outras notas

Concentration: Please refer to lot specific datasheet.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable