MABC140

Anti-ARC Antibody, clone 6F9.1

clone 6F9.1, from mouse

• Sinônimo(s): Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Arg3.1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• clone: 6F9.1, monoclonal
• application: IHC; WB
• reatividade de espécies: human
• técnica(s): immunohistochemistry: suitable (paraffin); western blot: suitable

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 6F9.1, monoclonal
• reatividade de espécies: human
• técnica(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_056008
• nº de adesão UniProt: Q7LC44
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ARC(23237)

Descrição

Descrição geral

Activity-regulated cytoskeleton-associated protein (ARC), also known as Activity-regulated gene 3.1 protein homolog (ARG3.1), plays an important role in synaptic plasticity and the formation of long-term memory. ARC is enriched in the postsynaptic density of dendritic spines and regulates endocytosis of AMPA receptors in response to synaptic activity and is required for homeostatic synaptic scaling of AMPA receptors. ARC also plays a role in the regulation of cell morphology, cytoskeletal organization, stress fiber dynamics, and cell migration.

Imunogênio

GST-tagged recombinant protein corresponding to human ARC.

Aplicação

Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, that targets ARC & has been tested in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ARC in human brain tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualidade

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected ARC in 200 µg of human hippocampus tissue lysate.

Descrição-alvo

~ 45 kDa observed

forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Human hippocampus tissue lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable