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MAB5200

Sigma-Aldrich

Anti-Synaptotagmin I Antibody

Chemicon®, from mouse

Sinônimo(s):

p65, Syt1

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

monoclonal

reatividade de espécies

frog, bovine, chicken, rabbit, rat, shark, mouse

fabricante/nome comercial

Chemicon®

técnica(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG2a

nº de adesão NCBI

NM_005639.1

nº de adesão UniProt

P21579

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... SYT1(6857)

Especificidade

Synaptotagmin 1, also known as p65. By Western blot MAB5200 reacts with a single protein with a molecular weight of approximately 65 kDa. MAB5200 has not been epitope mapped.

Imunogênio

Rat brain synaptotagmin.

Aplicação

Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Synaptotagmin I Antibody is validated for use in IP, WB, IC for the detection of Synaptotagmin I.
Western blot: 5 μg/mL (colormetric) Immunocytochemistry

Immunoprecipitation

Optimal working dilutions and protocols must be determined by the end user.

forma física

Format: Purified
Purified immunoglobulin. Liquid in PBS with 50% glycerol and 0.09% sodium azide.

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots up to 12 months.Avoid repeated freeze/thaw cycles.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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M Shao et al.
Neuroscience, 161(4), 988-1007 (2009-04-21)
Vestibular compensation refers to the behavioral recovery after a unilateral peripheral vestibular lesion. In chickens, posture and balance deficits are present immediately following unilateral vestibular ganglionectomy (UVG). After three days, most operated chickens begin to recover, but severe deficits persist
B Marquèze et al.
Biochimie, 82(5), 409-420 (2000-06-24)
The aim of this review is to give a broad picture of what is actually known about the synaptotagmin family. Synaptotagmin I is an abundant synaptic vesicle and secretory granule protein in neurons and endocrine cells which plays a key
AMPA receptor subunit expression in chick vestibular nucleus neurons.
Anastas Popratiloff, Ya-Xian Wang, Jared Narvid, Ronald S Petralia, Christian Giaume et al.
Journal of Neuroscience Research null
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue
Matthew, W D, et al
The Journal of cell biology, 91, 257-269 (1981)
M Shao et al.
Neuroscience, 223, 333-354 (2012-08-09)
Unilateral damage to the peripheral vestibular receptors precipitates a debilitating syndrome of oculomotor and balance deficits at rest, which extensively normalize during the first week after the lesion due to vestibular compensation. In vivo studies suggest that GABA(B) receptor activation
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