MAB1307
Mouse Anti-Human IgG1 Antibody, clone HP6001, Fc
clone HP6001, Chemicon®, from mouse
Sinônimo(s):
Anti-CD32, Anti-FCG2, Anti-FCGR2, Anti-FCGR2C, Anti-FcGRIIB, Anti-FcRII-c, Anti-FcgammaRIIb, Anti-IGFR2
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.46
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
secondary antibodies
clone
HP6001, monoclonal
reatividade de espécies
human
fabricante/nome comercial
Chemicon®
técnica(s)
ELISA: suitable
radioimmunoassay: suitable
western blot: suitable
Isotipo
IgG2b
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... FCGR2B(2213)
Categorias relacionadas
Especificidade
Human IgG1 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 100% human IgG subclass 2- 0.25% human IgG subclass 3- 0.01%
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
Imunogênio
Epitope: Fc fragment
Aplicação
Detect Human IgG1 using this Mouse anti-Human IgG1 Antibody, clone HP6001, Fc validated for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG1 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Ligação
Replaces: MABN1055
forma física
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl containing 0.1% sodium azide.
Armazenamento e estabilidade
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Lei Tian et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 28(1), 201-214 (2021-10-15)
mAbs blocking immune checkpoints have emerged as important cancer therapeutics, as exemplified by systemic administration of the IgG1 anti-CD47 mAb that blocks the "don't eat me" pathway. However, this strategy is associated with severe toxicity. To improve therapeutic efficacy while
Suzanne E Barbour et al.
Infection and immunity, 70(6), 2780-2786 (2002-05-16)
Several lines of evidence indicate that the monocytes of subjects with localized juvenile periodontitis (LJP) are functionally distinct from cells of age- and race-matched nonperiodontitis (NP) subjects. Among the abnormalities are the propensity to secrete large amounts of prostaglandin E(2)
R C Williams et al.
Arthritis and rheumatism, 40(1), 109-123 (1997-01-01)
To characterize immunologic specificity and possible antiidiotype activity of IgG anti-F(ab')2 in normal subjects as well as in patients with active and inactive systemic lupus erythematosus (SLE). IgG anti-F(ab')2 and anti-double-stranded DNA (anti-dsDNA) were affinity isolated from immunoadsorption columns of
Monoclonal antibody-based solid-phase immunoenzymometric assays for quantifying human immunoglobulin G and its subclasses in serum.
Papadea, C, et al.
Clinical Chemistry, 31, 1940-1945 (1985)
C B Reimer et al.
Hybridoma, 3(3), 263-275 (1984-01-01)
Stable clones of 31 mouse hybridomas that produce monoclonal antibodies (MAbs) against human IgG antigenic determinants were obtained. The number of hybridomas of different specificity described are: 2 anti-IgG1 Fc, 1 anti-IgG2 Fc, 1 anti-IgG2 Fd, 2 anti-IgG3 Fc, 2
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