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Merck

FCGR2B

Fc fragment of IgG, low affinity IIb, receptor (CD32)

Synonyms:
CD32, CD32B, FCG2, FCGR2, IGFR2
Species:
Human FCGR2B (2213), Mouse Fcgr2b (14130), Rat Fcgr2b (289211), sheep FCGR2B (100192432), domestic cat FCGR2B (101087550)
UniProtKB ID:
P31994, A6H8N3, O95649, Q53X85, Q5VXA9, Q8NIA1
Gene ID:
  • Human(2213) Summary: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • Mouse(14130) Fc receptor, IgG, low affinity IIb
  • Rat(289211) Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • sheep(100192432) Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • domestic cat(101087550) Fc fragment of IgG, low affinity IIb, receptor (CD32)

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ELISA

Product Number
Description
Species
RAB0181
Human FcgRIIBC ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
RAB0559
Mouse Fcgr2b ELISA Kit, for serum, plasma and cell culture supernatants,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
MAB1302
Mouse Anti-Human IgG Antibody, clone HP6017, Fc, clone HP6017, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
radioimmunoassay
western blot
MAB1308
Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc, clone HP6002, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
radioimmunoassay
western blot
SAB4301244
Anti-phospho-CD32 (pTyr292) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
SAB4504023
Anti-phospho-CD32 (pTyr292) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
SAB1405802
Anti-FCGR2B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP6396
Fc-gamma RIIB/CD32b human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU117131
MISSION® esiRNA, targeting human FCGR2B, FCGR2C,
Species
human
EMU066301
MISSION® esiRNA, targeting mouse Fcgr2b,
Species
mouse