MAB1096
Anti-Tumor Necrosis Factor-α Antibody, clone 195
clone 195, Chemicon®, from mouse
Sinônimo(s):
TNF-alpha
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
195, monoclonal
reatividade de espécies
human
não deve reagir com
pig, monkey, canine, mouse, rat, baboon
embalagem
antibody small pack of 25 μg
fabricante/nome comercial
Chemicon®
técnica(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
neutralization: suitable
western blot: suitable
Isotipo
IgG3
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... TNF(7124)
Especificidade
The antibody reacts with human, natural and recombinant TNF-alpha. lt does not react with human TNF-beta (lymphotoxin). lt does not react with TNF-alpha from mouse, rat, canine, porcine, rhesus-monkey or baboon.
SPECIES REACTIVITIES:
Not mouse, rat, canine, porcine, baboon or rhesus-monkey.
SPECIES REACTIVITIES:
Not mouse, rat, canine, porcine, baboon or rhesus-monkey.
Imunogênio
Human, recombinant tumor necrosis factor-alpha produced in E. coli.
Aplicação
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
This Anti-Tumor Necrosis Factor-α Antibody, clone 195 is validated for use in IC, IH, NEUT, WB for the detection of Tumor Necrosis Factor-α.
Western Blot
Immunocytochemistry
Immunohistochemistry
Neutralization: 50 ng of TNF-alpha antibody is required for the neutralization of 1 U TNF-alpha. The TNF-alpha-preparation which is used has a specific activity of 2 x 10(7) U/mg protein [cell lytic assay with L929 cells (mouse transformed fibroblasts) and/or WEHJ 164 cells (mouse fibrosarcoma cells)/actinomycin D].
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Immunohistochemistry
Neutralization: 50 ng of TNF-alpha antibody is required for the neutralization of 1 U TNF-alpha. The TNF-alpha-preparation which is used has a specific activity of 2 x 10(7) U/mg protein [cell lytic assay with L929 cells (mouse transformed fibroblasts) and/or WEHJ 164 cells (mouse fibrosarcoma cells)/actinomycin D].
Optimal working dilutions must be determined by end user.
Ligação
Replaces: 04-1114
forma física
Format: Purified
Purified immunoglobulin. Liquid in 0.01M PBS pH 7.1, 0.15M NaCl containing no preservatives. Sterile filtered.
Armazenamento e estabilidade
Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Freeze only once.
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Robert A Cox, Ann S Burke, Gloria Oliveras, Perenlei Enkhbaatar, Lillian D Traber et al.
Experimental Lung Research null
Monocyte-mediated drug-dependent cellular cytotoxicity: effects on different WEHI 164 target cell lines.
Austgulen, R, et al.
Cancer Immunology, Immunotherapy, 22, 176-180 (1986)
Human lymphotoxin.
Aggarwal, B B
Test, 116, 441-448 (1985)
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