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Merck
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Key Documents

GF333

Sigma-Aldrich

IL-2,
Human Recombinant Animal Free

Sinônimo(s):

Interleukin-2, IL2

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About This Item

Código UNSPSC:
12352202
eCl@ss:
32160405

Impurezas

<0.1 μg/mg protein endotoxin (<1 EU/μg)

Nível de qualidade

nº de adesão UniProt

Condições de expedição

wet ice

Categorias relacionadas

Descrição geral

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Recombinant human IL-2 is a 15.5kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.
Product Source: Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.

Aplicação

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Qualidade

Determined its its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.

forma física

Product is presented without additives and is filtered through a 0.2 micron filter before lyophilization.

Armazenamento e estabilidade

Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in 100mM Acetic Acid to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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