GF313
TGF- α Protein, Human Recombinant Animal Free
>98% (SDS-PAGE and HPLC), <0.1 μg/mg protein endotoxin (<1EU/μg)
Sinônimo(s):
Transforming growth factor alpha, TGFa, TGF alpha, EGF-like TGF, TGF type 1
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About This Item
Produtos recomendados
recombinante
expressed in E. coli
Nível de qualidade
Ensaio
>98% (SDS-PAGE and HPLC)
Impurezas
<0.1 μg/mg protein endotoxin (<1EU/μg)
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
Descrição geral
Product Source: E. coli
Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Especificidade
Cross Reactivty
Chicken, Mouse, Rat
Chicken, Mouse, Rat
Aplicação
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Qualidade
Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
forma física
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human TGF- α is manufactured using all non-animal reagents
Armazenamento e estabilidade
Store at -20°C for up to 6 months from date of receipt.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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