ABN131
Anti-GABA Antibody
from rabbit, purified by affinity chromatography
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
rat
reatividade da espécie (prevista por homologia)
all
técnica(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
rat ... Gabra1(29705)
Descrição geral
Neurotransmitters can be defined as chemical substances that are released by the presynaptic neuron before being bound by receptors on the postsynaptic cell surface. It has been well established that the nervous system utilizes neurotransmitters for cell signaling. Neurotransmitters can be divided into two groups; low molecular weight transmitter molecules such as biogenic amines, purines, or amino acids, and bioactive peptides, of which more than 50 members have been identified in the mammalian central nervous system. Many low molecular weight neurotransmitters are produced within the axon terminal from common cellular metabolites and packaged into synaptic vesicles. The transport and delivery of vesicles containing neurotransmitter is a highly regulated and complex process. GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system that is involved in the pathogenesis of certain neurological and psychiatric disorders. GABA is produced from glutamic acid in a reaction catalyzed by glutamic acid decarboxylase. GABA interacts with the GABAA and GABAB receptors, which are widely distributed throughout the nervous system and in a variety of cell types. The immunolocalization, neuronal distribution, and vesicular compartmentalization of neurotransmitter molecules and their precursors are important for understanding the modulation, regulation, and function of neurotransmitters in the nervous system.
Aplicação
Anti-GABA Antibody is a highly specific rabbit polyclonal antibody, that targets GABA & has been tested in IHC (Paraffin) & Enzyme Immunoassay (ELISA).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA in rat brain tissue (Note: Non-specific staining may be observed in vascular tissues.).
ELISA Analysis: A representative lot from an independent laboratory detected GABA in a competitive ELISA.
ELISA Analysis: A representative lot from an independent laboratory detected GABA in a competitive ELISA.
Qualidade
Evaluated by Immunohistochemistry (Paraffin) in Rat brain tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected GABA in Rat brain tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected GABA in Rat brain tissue sections.
Ligação
Replaces: AB131
Nota de análise
Control
Rat hypothalamus tissue
Rat hypothalamus tissue
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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