ABF219

Anti-SARM Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: human
• técnica(s): immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• nº de adesão UniProt: Q6SZW1
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SARM1(23098)

Descrição

Descrição geral

Sterile alpha and Armadillo repeat protein (SARM), also known as Sterile alpha and TIR motif-containing protein 1 (SARM1) and Sterile alpha motif domain-containing protein 2 (SAMD2), is involved in the innate immnune response. SARM blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. SARM is expressed kidney and liver with lower levels found in placenta.

Especificidade

This antibody recognizes the C-terminus of SARM.

Imunogênio

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human SARM.

Aplicação

Detect Sterile alpha & Armadillo repeat protein using this rabbit polyclonal antibody, Anti-SARM Antibody validated for use in western blotting, ICC & Immunofluorescence.

Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualidade

Evaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected SARM in 15 µg of Daudi cell lysate.

Descrição-alvo

~89 kDa observed. Uncharacterized bands may appear in some lysates.

forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Daudi cell lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable