Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

AB9870

Sigma-Aldrich

Anti-STIM1 Antibody

Chemicon®, from rabbit

Sinônimo(s):

Stromal interaction molecule 1

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
clone:
polyclonal
application:
WB
reatividade de espécies:
human, mouse
técnica(s):
western blot: suitable
citations:
9

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

human, mouse

fabricante/nome comercial

Chemicon®

técnica(s)

western blot: suitable

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

Descrição geral

TRP (transient receptor potential)-related ion channels (TRPCs) have been postulated as candidates for forming both receptor-operated (ROCE) and capacitative Ca2+ entry channels across the plasma membrane. ER transmembrane protein STIM1 senses the depletion of Ca2+ from ER stores. Orai proteins, interacting with TRPCs, act as regulatory subunits that confers STIM1-mediated store depletion sensitivity to these channels and regulate Ca2+ influx through the plasma membrane.

Especificidade

Catalogue No. AB9870 recognizes the C-Terminus of STIM1.

Imunogênio

Synthetic Linear Peptide

Aplicação

Anti-STIM1 Antibody is an antibody against STIM1 for use in WB.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Qualidade

Routinely evaluated in western blotting using Jurkat lysate.

Descrição-alvo

80 kDa

forma física

Format: Purified
Protein A purified
Purified in PBS with 0.05% NaN3

Armazenamento e estabilidade

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Nota de análise

Control
Jurkat lysate.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Não está encontrando o produto certo?  

Experimente o nosso Ferramenta de seleção de produtos.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Julie Perroud et al.
Journal of cell science, 130(18), 3083-3093 (2017-08-02)
Ca2+ signaling plays a key role during human myoblast differentiation. Among Ca2+-sensitive pathways, calcineurin is essential for myoblast differentiation and muscle regeneration. Nuclear factor of activated T-cell (NFAT) transcription factors are the major calcineurin targets. We investigated the expression and
Paula Nunes-Hasler et al.
Nature communications, 8(1), 1852-1852 (2017-11-28)
Antigen cross-presentation by dendritic cells (DC) stimulates cytotoxic T cell activation to promote immunity to intracellular pathogens, viruses and cancer. Phagocytosed antigens generate potent T cell responses, but the signalling and trafficking pathways regulating their cross-presentation are unclear. Here, we
Ling Lin et al.
Theranostics, 11(9), 4232-4250 (2021-03-24)
Background: Spectrin, beta, non-erythrocytic 1 (SPTBN1), an adapter protein for transforming growth factor beta (TGF-β) signaling, is recognized as a tumor suppressor in the development of hepatocellular carcinoma (HCC); however, the underlying molecular mechanisms of this tumor suppression remain obscure.
Agnieszka Dyrda et al.
Cell calcium, 86, 102134-102134 (2019-12-16)
During myogenesis, a long splice variant of STIM1, called STIM1L is getting expressed, while the level of STIM1 remains constant. Previous work demonstrated that STIM1L is more efficient in eliciting store-operated Ca2+ entry (SOCE), but no current analysis of the

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica