8.53022

Boc-Trp(For)-OH

Novabiochem^®

• Sinônimo(s): Boc-Trp(For)-OH, N-α-t.-Boc-N-in-formyl-L-tryptophan
• Fórmula empírica (Notação de Hill): C₁₇H₂₀N₂O₅
• Número CAS: 47355-10-2
• Peso molecular: 332.35
• Número MDL: MFCD00065992
• Código UNSPSC: 12352209
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• linha de produto: Novabiochem^®
• Ensaio: ≥98% (TLC)
• Formulário: powder
• adequação da reação: reaction type: Boc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• pf: 100 °C (decomposition)
• aplicação(ões): peptide synthesis
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C17H20N2O5/c1-17(2,3)24-16(23)18-13(15(21)22)8-11-9-19(10-20)14-7-5-4-6-12(11)14/h4-7,9-10,13H,8H2,1-3H3,(H,18,23)(H,21,22)/t13-/m0/s1
• chave InChI: IHXHBYFWSOYYTR-ZDUSSCGKSA-N

Descrição

Descrição geral

Standard building block for introduction of tryptophan by Boc SPPS. The formyl group is stable to standard high HF cleavage but can be removed by HF containing thiophenol ^[1,2,3]. The formyl group can also be removed with piperidine in DMF prior to HF cleavage.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] M. Ohno, et al. (1973) Bull. Chem. Soc. Jpn., 46, 3280.
^[2] W. F. Heath, et al. (1982) J. Chem. Soc., Chem. Commun., 896.
^[3] G. R. Matsueda (1982) Int. J. Peptide Protein Res., 20, 26.

Ligação

Replaces: 04-12-0087

Nota de análise

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Purity (TLC(011A)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable