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Merck
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Key Documents

407125

Sigma-Aldrich

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays

Major phosphorus compound in plants that chelates with a variety of di- and trivalent cations.

Sinônimo(s):

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays, D-Ins(1,2,3,4,5,6)P₆, 12Na, Phytic Acid, 12Na

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About This Item

Fórmula empírica (Notação de Hill):
C6H6O24P6 · 12Na
Número CAS:
Peso molecular:
923.82
Código UNSPSC:
12352211
NACRES:
NA.77

Nível de qualidade

Ensaio

≥85% (HPLC)

forma

solid

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
desiccated (hygroscopic)

cor

white to off-white

solubilidade

water: 1 mg/mL

Condições de expedição

ambient

temperatura de armazenamento

−20°C

InChI

1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12

chave InChI

KETSPIPODMGOEJ-UHFFFAOYSA-B

Descrição geral

Major phosphorus compound in plants that chelates with a variety of di- and trivalent cations. Reported to suppress damaging iron-catalyzed redox reactions.
Major phosphorus compound in plants. Chelates with a variety of di- and trivalent cations. Inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Also reported to suppress damaging iron-catalyzed redox reactions.

Ações bioquímicas/fisiológicas

Cell permeable: no
Primary Target
Chelates with a variety of di- and trivalent cations
Product does not compete with ATP.
Reversible: no

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Outras notas

Shamsuddin, A.M., and Yang, G.Y. 1995. Carcinogenesis 16, 1975.
Graf, E., and Eaton, J.W. 1993. Nutr. Cancer19, 11.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Hayley Whitfield et al.
The Biochemical journal, 477(14), 2621-2638 (2020-07-25)
Inositol polyphosphates are ubiquitous molecular signals in metazoans, as are their pyrophosphorylated derivatives that bear a so-called 'high-energy' phosphoanhydride bond. A structural rationale is provided for the ability of Arabidopsis inositol tris/tetrakisphosphate kinase 1 to discriminate between symmetric and enantiomeric
Yann Desfougères et al.
Methods in molecular biology (Clifton, N.J.), 2091, 59-71 (2019-11-28)
The yeast Saccharomyces cerevisiae has given us much information on the metabolism and function of inositol polyphosphates and inorganic polyphosphate. To expand our knowledge of the metabolic as well as functional connections between inositol polyphosphates and inorganic polyphosphate, we have

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