371754
Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb
liquid, Calbiochem®
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
purified antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
forma
liquid
não contém
preservative
reatividade de espécies
human, mouse, rat
fabricante/nome comercial
Calbiochem®
condição de armazenamento
OK to freeze
avoid repeated freeze/thaw cycles
Isotipo
IgG
Condições de expedição
wet ice
temperatura de armazenamento
−70°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... GNAI1(2770)
mouse ... Gnai1(14677)
rat ... Gnai1(25686)
Descrição geral
Anti-Gqα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa Gqα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.
Protein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins.
Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.
Imunogênio
a synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
Aplicação
Immunoblotting (1:1000)
Neutralization Studies (see comments)
Neutralization Studies (see comments)
Advertência
Toxicity: Standard Handling (A)
Outras notas
The antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407.
Informações legais
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
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