345802

Gc-Globulin, Mixed Type, Human Plasma

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

• Sinônimo(s): Gc-Globulin, Mixed Type, Human Plasma
• Número CAS: 68476-36-8
• Número MDL: MFCD18251359
• Código UNSPSC: 12352202
• NACRES: NA.25

Propriedades

• fonte biológica: human plasma
• Nível de qualidade: 100
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Native Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.

Aplicação

Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.

Advertência

Toxicity: Standard Handling (A)

forma física

Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Nota de preparo

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstituição

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.

Outras notas

Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3