14-683-M
PAK3 Protein, active, 10 µg
Active, C-terminal 6His-tagged, recombinant, human full length, PAK3. For use in Kinase Assays.
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About This Item
Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Produtos recomendados
fonte biológica
human
Nível de qualidade
100
300
recombinante
expressed in baculovirus infected Sf21 cells
peso molecular
Mw 63.2 kDa
fabricante/nome comercial
Upstate®
técnica(s)
activity assay: suitable (kinase)
nº de adesão NCBI
nº de adesão UniProt
Informações sobre genes
human ... PAK3(5063)
Descrição geral
C-terminal 6His-tagged, recombinant, human full length, PAK3.
mitosis
mitosis
Product Source: PAK3 expressed by baculovirus in Sf21 cells.
Aplicação
Research Category
Inflammation & Immunology
Inflammation & Immunology
Ações bioquímicas/fisiológicas
Protein Target: PAK3
Target Sub-Family: STE
Qualidade
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
forma física
Ni2+/NTA-agarose
Armazenamento e estabilidade
6 months at -70°C from date of shipment
Outras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Skin Sens. 1
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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J Roig et al.
Vitamins and hormones, 62, 167-198 (2001-05-11)
The p21-activated protein kinase gamma-PAK, also known as PAK2, has very different properties from the other two highly conserved isoforms of the PAK family, alpha-PAK (PAK1) and beta-PAK (PAK3). gamma-PAK has cytostatic activity, as shown by inhibition of cleavage of
Ger J A Ramakers
Trends in neurosciences, 25(4), 191-199 (2002-05-10)
For several decades, it has been known that mental retardation (MR) is associated with abnormalities in dendrites and dendritic spines. The recent cloning of seven genes that cause nonspecific MR when mutated provides important insights in the cellular mechanisms that
Rho proteins, mental retardation and the neurobiological basis of intelligence.
van Galen, Elly J M and Ramakers, Ger J A
Progress in Brain Research, 147, 295-317 (2005)
Zahara M Jaffer et al.
The international journal of biochemistry & cell biology, 34(7), 713-717 (2002-04-16)
The p21-activated kinases (Paks) are serine/threonine protein kinases that bind to and, in some cases, are stimulated by activated forms of the small GTPases, Cdc42 and Rac. With the recent discovery of several novel isoforms, Paks are now categorized into
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