Pular para o conteúdo
Merck
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Documentos Principais

14-155

Sigma-Aldrich

Histone H1 Protein, 20 mg

Purified bovine Histone H1 protein for use as a substrate in histone modification assays (HAT, HDAC, DNMT) and chromatin assembly studies.

Sinônimo(s):

Linker Histone H1

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About This Item

Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32

fonte biológica

bovine

Nível de qualidade

peso molecular

Mw 32 kDa

fabricante/nome comercial

Upstate®

técnica(s)

activity assay: suitable (kinase)

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

Descrição geral

H1 and related linker histones are important both for maintenance of higher-order chromatin structure and for the regulation of gene expression. Nucleosomal stabilization is provided through the binding of histone H1 to the nucleosomal dyad and the linker DNA entering and exiting the core particle. Additional experimental evidence illustrates the influence of histone H1 on chromatin arrangement and compaction. The family of histone H1 proteins contains five somatic variants (H1.1, H1.2, H1.3, H1.4 and H1.5) which are expressed in nearly all cell types.
Product Source: Lysine rich fraction from calf thymus

Qualidade

Routinely evaluated by Kinase assay using cdk2/cyclin A, active (14-448) to phosphorylate Histone H1.

forma física

Sterilized through a 0.2 micron membrane filter

Armazenamento e estabilidade

1 year at -20°C

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
This product is derived from bovine source. Export of this product to certain countries may be restricted. Please contact Customer Service or your local distributor to inquire about product availability and export options.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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