1.16177

LiChrospher^® 100 RP-18 (5 µm) HPLC Columns

HPLC sorbent

• Sinônimo(s): TM=["LiChrospher"] C18 sorbent for HPLC
• Código UNSPSC: 41115709
• NACRES: SB.52

Propriedades

• Nome do produto: LiChrospher^® 100 RP-18 (5 µm),
• Materiais: stainless steel column
• Agency: suitable for USP L1
• linha de produto: LiChrospher^®
• Características: endcapped: no
• embalagem: 1 ea of
• Extensão da rotulagem: 21% Carbon loading
• Parâmetros: 60 °C max. temp.
• técnica(s): HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• área da superfície: 350 m²/g
• Matriz: fully porous particle
• Grupo ativo da matriz: C18 bonding phase
• tamanho de partícula: 5 μm
• tamanho de poro: 100 Å pore size
• Faixa de pH operacional: 2-7.5
• densidade volumétrica: 200‑400 kg/m³
• técnica de separação: reversed phase
• temperatura de armazenamento: no temp limit

Descrição

Descrição geral

LiChrospher^® RP-18 is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Aplicação

• Fast Determination of a Novel Iron Chelate Prototype Used as a Fertilizer by Liquid Chromatography Coupled to a Diode Array Detector.: This study explores the use of LiChrospher^® 100 RP-18 (5 µm) for the rapid analysis of a new iron chelate fertilizer, showcasing its effectiveness in agricultural applications (Valverde et al., 2021).


• Application of Chemometric Approach for Development and Validation of High-Performance Liquid Chromatography Method for Estimation of Ropinirole Hydrochloride.: The research utilizes LiChrospher^® 100 RP-18 (5 µm) for the quantification of ropinirole in pharmaceutical formulations, highlighting its precision and robustness (Fatima et al., 2019).


• Quantification of Alprenolol and Propranolol in Human Plasma Using a Two-Dimensional Liquid Chromatography (2D-LC).: This paper demonstrates the application of LiChrospher^® 100 RP-18 (5 µm) in clinical settings for the analysis of beta-blockers in plasma, indicating its utility in pharmacokinetics (Gonçalves et al., 2017).


• Ultrasound-Assisted Surfactant-Enhanced Emulsification Micro-Extraction Followed by HPLC for Determination of Preservatives in Water, Beverages, and Personal Care Products.: The study highlights the use of LiChrospher^® 100 RP-18 (5 µm) for environmental and quality control analyses, demonstrating its versatility in various matrices (Jan-E et al., 2017).


• Development and Validation of Stability-Indicating HPLC Method for Determination of Cefpirome Sulfate.: This research focuses on the stability testing of cefpirome using LiChrospher^® 100 RP-18 (5 µm), emphasizing its reliability for pharmaceutical quality control (Zalewski et al., 2014).

Nota de análise

Application test: passes test
Pressure: ≤ 35 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
separation factor (Acetophenone/Phenol, selectivity test): 2.05 - 2.25
separation factor (Acetophenone/Cinnamic acid, selectivity test): 1.24 - 1.37
capacity factor (Toluene): 13.0 - 18.0

Informações legais

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable